Defectos de la apoptosis en el linfoma cutáneo

Autores/as

  • María Adelaida Quijano
  • Margarita María Velásquez

DOI:

https://doi.org/10.29176/2590843X.293

Palabras clave:

linfoma, cutáneo, células B, células T, apoptosis, vía, intrínseca, extrínseca, tratamiento

Resumen

Los linfomas cutáneos primarios se definen como linfomas no Hodgkin que se presentan en la piel, sin evidencia extracutánea de la enfermedad en el momento del diagnóstico y, como regla general, permanecen allí durante al menos seis meses. Diferentes alteraciones de las vías de la apoptosis son responsables en gran medida de la patogénesis de los linfomas cutáneos. Los enfoques terapéuticos futuros deben apuntar a restaurar la expresión del receptor de la muerte, que se deben combinar con moduladores de moléculas inhibidoras y con estimuladores de los demás mecanismos implicados en la apoptosis.

Biografía del autor/a

María Adelaida Quijano

Médica, residente de Dermatología, Sección de Dermatología, Universidad de Antioquia, Medellín, Colombia

Margarita María Velásquez

Dermatóloga, Ph.D. en Ciencias Básicas Biomédicas; docente de Dermatología, Universidad de Antioquia; Centro de Investigaciones Dermatológicas, CIDERM, Sección de Dermatología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.

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Cómo citar

1.
Quijano MA, Velásquez MM. Defectos de la apoptosis en el linfoma cutáneo. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 1 de julio de 2016 [citado 28 de marzo de 2024];24(3):174-85. Disponible en: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/293

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2016-07-01

Cómo citar

1.
Quijano MA, Velásquez MM. Defectos de la apoptosis en el linfoma cutáneo. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 1 de julio de 2016 [citado 28 de marzo de 2024];24(3):174-85. Disponible en: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/293

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