Emperipolesis
Keywords:
emperipolesis, claves dermatopatológicasAbstract
La emperipolesis es la capacidad que tienen los linfocitos, plasmocitos y polimorfonucleares de penetrar al citoplasma de otras células, usualmente gigantes, sin sufrir daño en el proceso. Su significado es desconocido. Es un rasgo morfológico muy útil en el diagnóstico histopatológico de algunas enfermedades como la de Rosai-Dorfman, la micosis fungoide granulomatosa, el chalazion, la paniculitis histiocítica citofágica y otras más. Ilustramos el fenómeno en las 3 primeras entidades mencionadas.
Author Biographies
Sandra Liliana Cortés Vera, Universidad Nacional
R III Dermatología, Universidad Nacional de Colombia, Bogotá.
Gerzain Rodríguez Toro, Universidad Nacional
Profesor titular de Patología, Facultad de Medicina, Universidad Nacional de Colombia, Jefe de Patología, Instituto Nacional de Salud, Bogotá.
References
1. McFarland W. Emperipolesis. N Engl J Med 1970; 282: 168.
https://doi.org/10.1056/NEJM197001152820319
2. De Pasquale A, Paterlini P, Quaglino D. Emperipolesis of granulocytes within megakaryocytes. Br J Hematol 1985; 60:384-386.
https://doi.org/10.1111/j.1365-2141.1985.tb07429.x
3. Sherwin RP, Margolick JB. Emperipolesis or phagocitosis by Reed-Sternberg cells. N Engl J Med 1979; 301:1348-1349.
https://doi.org/10.1056/NEJM197912133012419
4. Schumacher HR, Szekely IE , Fischer DR. Letter: Research, serendipity and emperipolesis. Lancet 1974; 1 :812.
https://doi.org/10.1016/S0140-6736(74)92883-9
5. LeBoit PE, Zackheim HS, White CR. Granulomatous variants of cutaneous T-cell lymphoma. The histopathology of granulomatous mycosis fungoides and granulomatous slack skin. Am J Surg Pathol 1988; 12:83-95.
https://doi.org/10.1097/00000478-198802000-00002
6. Rosai J, Dorfman RF. Sinus histiocytosis with lymphadenopathy. Arch Pathol 1969; 87: 63-70.
7. Annessi G, Gianetti A. Purely cutaneous RosaiDorfman disease. Br J Dermatol 1996; 134:749-753.
https://doi.org/10.1111/j.1365-2133.1996.tb06984.x
8. Chen KR , Tanaka M, Miyakawa S. Granulomatous mycosis fungoides with small intestinal involvement and a fatal outcome. Br J Dermatol 1998; 138:522-525.
https://doi.org/10.1046/j.1365-2133.1998.02138.x
9. Metzler G, Schlagenhauff B, Krober SM , et al. Granulomatous mycosis fungoides: report of a case with sorne features of granulomatous slack skin. Am J Dermatopathol 1999; 21:156-160.
https://doi.org/10.1097/00000372-199904000-00008
10. Alegre V, Winkelmann RK. Histiocytic cytophagic panniculitis. J Am Acad Dermatol 1989; 20:177-185.
https://doi.org/10.1016/S0190-9622(89)70018-9
11. Perrin C, Michiels JF, Lacar JP, et al. Sinus histiocytosis (Rosai-Dorfman disease) clinically limited to the skin. An immunohistochemical and ultrastructural study. J Cutan Pathol 1993; 20:368-374.
https://doi.org/10.1111/j.1600-0560.1993.tb01278.x
https://doi.org/10.1056/NEJM197001152820319
2. De Pasquale A, Paterlini P, Quaglino D. Emperipolesis of granulocytes within megakaryocytes. Br J Hematol 1985; 60:384-386.
https://doi.org/10.1111/j.1365-2141.1985.tb07429.x
3. Sherwin RP, Margolick JB. Emperipolesis or phagocitosis by Reed-Sternberg cells. N Engl J Med 1979; 301:1348-1349.
https://doi.org/10.1056/NEJM197912133012419
4. Schumacher HR, Szekely IE , Fischer DR. Letter: Research, serendipity and emperipolesis. Lancet 1974; 1 :812.
https://doi.org/10.1016/S0140-6736(74)92883-9
5. LeBoit PE, Zackheim HS, White CR. Granulomatous variants of cutaneous T-cell lymphoma. The histopathology of granulomatous mycosis fungoides and granulomatous slack skin. Am J Surg Pathol 1988; 12:83-95.
https://doi.org/10.1097/00000478-198802000-00002
6. Rosai J, Dorfman RF. Sinus histiocytosis with lymphadenopathy. Arch Pathol 1969; 87: 63-70.
7. Annessi G, Gianetti A. Purely cutaneous RosaiDorfman disease. Br J Dermatol 1996; 134:749-753.
https://doi.org/10.1111/j.1365-2133.1996.tb06984.x
8. Chen KR , Tanaka M, Miyakawa S. Granulomatous mycosis fungoides with small intestinal involvement and a fatal outcome. Br J Dermatol 1998; 138:522-525.
https://doi.org/10.1046/j.1365-2133.1998.02138.x
9. Metzler G, Schlagenhauff B, Krober SM , et al. Granulomatous mycosis fungoides: report of a case with sorne features of granulomatous slack skin. Am J Dermatopathol 1999; 21:156-160.
https://doi.org/10.1097/00000372-199904000-00008
10. Alegre V, Winkelmann RK. Histiocytic cytophagic panniculitis. J Am Acad Dermatol 1989; 20:177-185.
https://doi.org/10.1016/S0190-9622(89)70018-9
11. Perrin C, Michiels JF, Lacar JP, et al. Sinus histiocytosis (Rosai-Dorfman disease) clinically limited to the skin. An immunohistochemical and ultrastructural study. J Cutan Pathol 1993; 20:368-374.
https://doi.org/10.1111/j.1600-0560.1993.tb01278.x
How to Cite
1.
Cortés Vera SL, Rodríguez Toro G. Emperipolesis. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2002 Feb. 1 [cited 2024 Jul. 3];10(1):693-6. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/617
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Published
2002-02-01
How to Cite
1.
Cortés Vera SL, Rodríguez Toro G. Emperipolesis. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2002 Feb. 1 [cited 2024 Jul. 3];10(1):693-6. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/617
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Continuing medical education
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