Digital ulcer as initial manifestation of limited systemic cutaneous scleroderma
Keywords:
Digital ulcer, anticentromere antibodies, sclerodermaAbstract
We report a case of a 68 years-old patient who presented with a digital ulcer as an initial expression of limited systemic scleroderma. It shows the importance of a dermatologist intervention with an adequate clinical history, physical examination, screening and clinical and pathological correlation to find an early diagnosis and to establish a suitable treatment in these patients.
Author Biographies
Claudia Marcela Arenas
Médica dermatóloga, Hospital Militar Central, Universidad Militar Nueva Granada, Bogotá, D.C., Colombia
Juliana Jiménez
Médica, residente de Dermatología de segundo año, Universidad Militar Nueva Granada, Bogotá, D.C., Colombia
María Isabel González
Médica dermatopatóloga, Hospital Militar Central, Universidad Militar Nueva Granada, Bogotá, D.C., Colombia
References
1. Balbir-Gurman, Moscovici Scleroderma: New aspects in pathogenesis and treatment. Best Pract Res Clin Rheumatol. 2012;26:13-24.
2. Grossman C, Dovrish Z, Shoenfeld Y, Amital H. Do infections facilitate the emergence of systemic sclerosis? Autoimmun Rev. 2011;10:244-7.
3. Arora-Singh RK, Assassi S, del Junco DJ, Arnett FC, Perry M, Irfan U. Autoimmune diseases and autoantibodies in the first degree relatives of patients with systemic sclerosis. J Autoimmun. 2010;35:52-7.
4. Avouac, Fransen, Walker, Riccieri, Smith. Preliminary criteria for the very early diagnosis of systemic sclerosis: Results of a Delphi Consensus Study from EULAR Scleroderma Trials and Research Group. Ann Rheum Dis. 2011;70:476-81.
5. Sachsenberg-Studer, Salomon, Prins, Saurat. Raynaud’s phenomenon, anticentromere antibodies, and digital necrosis without sclerodactyly: An entity independent of scleroderma? J Am Acad Dermatol. 2000;43:631-4.
6. Vayssairat M, Baudot N, Gaitz JP. Raynaud’s phenomenon together with antinuclear antibodies: A common subset of incomplete connective tissue disease. J Am Acad Dermatol. 1995;32:747-9.
7. Vayssairat M, Abuaf N, Baudot N, Deschamps A, Gaitz JP. Abnormal IgG cardiolipin antibody titers in patients with Raynaud’s phenomenon and/or related disorders: Prevalence and clinical significance. J Am Acad Dermatol. 1998;38:555
2. Grossman C, Dovrish Z, Shoenfeld Y, Amital H. Do infections facilitate the emergence of systemic sclerosis? Autoimmun Rev. 2011;10:244-7.
3. Arora-Singh RK, Assassi S, del Junco DJ, Arnett FC, Perry M, Irfan U. Autoimmune diseases and autoantibodies in the first degree relatives of patients with systemic sclerosis. J Autoimmun. 2010;35:52-7.
4. Avouac, Fransen, Walker, Riccieri, Smith. Preliminary criteria for the very early diagnosis of systemic sclerosis: Results of a Delphi Consensus Study from EULAR Scleroderma Trials and Research Group. Ann Rheum Dis. 2011;70:476-81.
5. Sachsenberg-Studer, Salomon, Prins, Saurat. Raynaud’s phenomenon, anticentromere antibodies, and digital necrosis without sclerodactyly: An entity independent of scleroderma? J Am Acad Dermatol. 2000;43:631-4.
6. Vayssairat M, Baudot N, Gaitz JP. Raynaud’s phenomenon together with antinuclear antibodies: A common subset of incomplete connective tissue disease. J Am Acad Dermatol. 1995;32:747-9.
7. Vayssairat M, Abuaf N, Baudot N, Deschamps A, Gaitz JP. Abnormal IgG cardiolipin antibody titers in patients with Raynaud’s phenomenon and/or related disorders: Prevalence and clinical significance. J Am Acad Dermatol. 1998;38:555
How to Cite
1.
Arenas CM, Jiménez J, González MI. Digital ulcer as initial manifestation of limited systemic cutaneous scleroderma. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Aug. 9 [cited 2024 Jul. 22];21(4):360-3. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/1029
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Published
2019-08-09
How to Cite
1.
Arenas CM, Jiménez J, González MI. Digital ulcer as initial manifestation of limited systemic cutaneous scleroderma. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Aug. 9 [cited 2024 Jul. 22];21(4):360-3. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/1029
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Section
Case Report
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