Generalized bullous pigmented fixed drug eruption

Authors

  • Lucía Giraldo
  • Joanna Cajamarca
  • Sandra Espinosa
  • Óscar Eduardo Mora

Keywords:

Adverse drug reaction, drug eruptions, trimethoprim-sulfamethoxazole.
Abstract Authors References How to Cite Downloads

Abstract

Fixed drug eruptions are reactions that can have a benign course or represent a life-threatening emergency. They are usually manifested two days after the administration of medications, as dark circumscribed macules leaving residual hyperpigmentation, being their hallmark the geographical memory. We report a case of generalized bullous pigmented fixed drug eruption in a patient treated with trimethoprim/sulfamethoxazole who had a good response to cutaneous and systemic management.

Author Biographies

Lucía Giraldo

Médicas, residentes de Dermatología, Fundación Universitaria de Ciencias de la Salud, Hospital de San José, Bogotá, D.C., Colombia

Joanna Cajamarca

Médicas, residentes de Dermatología, Fundación Universitaria de Ciencias de la Salud, Hospital de San José, Bogotá, D.C., Colombia.

Sandra Espinosa

Médicas, residentes de Dermatología, Fundación Universitaria de Ciencias de la Salud, Hospital de San José, Bogotá, D.C., Colombia.

Óscar Eduardo Mora

Médico dermatólogo; jefe, programa de Dermatología, Fundación Universitaria de Ciencias de la Salud, Hospital de San José, Bogotá, D.C., Colombia.

References

1. drug eruptions. Clin Geriatr Med. 2013;29:527-45.
2. Revuz J, Valeyrie-Allanore L. Drug reactions. In: Bolognia JL, Jorizzo JL, Schaffer JV, editors. Dermatology. Third edition. London: Elsevier Saunders; 2012. p. 335-56.
3. Lee CH, Chen YC, Cho YT, Chang CY, Chu CY. Fixed-drug eruption: A retrospective study in a single referral center in northern Taiwan. Dermatologica Sinica. 2012;30:11-5.
4. Hoetzenecker W, Nägeli M, Mehra ET, Jensen AN, Saulite I, Schmid-Grendelmeier P, et al. Adverse cutaneous drug eruptions: Current understanding. Semin Immunopathol. 2016;38:75-86.
5. Ôzkaya E. Oral mucosal fixed drug eruption: Characteristics and differential diagnosis. J Am Acad Dermatol. 2013;69:e51-8.
6. Dharamsi FM, Michener M, Dharamsi JW. Bullous fixed drug eruption masquerading as recurrent Stevens Johnson syndrome. J Emerg Med. 2015;48:551-4.

How to Cite

1.
Giraldo L, Cajamarca J, Espinosa S, Mora Óscar E. Generalized bullous pigmented fixed drug eruption. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Aug. 9 [cited 2024 Jul. 3];24(3):206-8. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/1111

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Published

2019-08-09

How to Cite

1.
Giraldo L, Cajamarca J, Espinosa S, Mora Óscar E. Generalized bullous pigmented fixed drug eruption. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Aug. 9 [cited 2024 Jul. 3];24(3):206-8. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/1111

Issue

Vol. 24 No. 3 (2016): July – September

Section

Case Report
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