Enfermedad de injerto contra huésped, una presentación inusual

Authors

  • Luz Adriana Vásquez Hospital Pablo Tobón Uribe
  • Andrés Mazo Universidad Pontificia Bolivariana
  • Ana Cristina Ruiz Hospital Pablo Tobón Uribe

DOI:

https://doi.org/10.29176/2590843X.13

Keywords:

Graft-versus-host, transplants

Abstract

The acute graft-versus-host disease is a common complication of allogeneic transplants with impact in morbidity and mortality. The dermatological and gastrointestinal manifestations are usually the most frequent and classical presentation; however, the dermatological signs are usually the earliest which is important for a timely diagnosis; the maculopapular rash is the most common dermatological manifestation. They have been described in the literature as lichenoid or alopecic plaques or just dyshidrosis. 
A case of hyperpigmented macules on the face is presented and it represents an atypical clinical form of this disease.

Author Biographies

Luz Adriana Vásquez, Hospital Pablo Tobón Uribe

Médica dermatóloga, Hospital Pablo Tobón Uribe, Medellín, Colombia

Andrés Mazo, Universidad Pontificia Bolivariana

Médico interno, Universidad Pontificia Bolivariana, Medellín, Colombia

Ana Cristina Ruiz, Hospital Pablo Tobón Uribe

Médica dermatopatóloga, Hospital Pablo Tobón Uribe, Medellín, Colombia

References

Jacobsohn DA, Vogelsang GB. Acute graft versus host disease. Orphanet J Rare Dis. 2007;2:35.

Montoya C, Sierra M, Vidal A. Enfermedad injerto contra huésped. Rev Colomb Dermatol. 2016;24:90-100.

Vigorito AC, Campregher PV, Storer BE, Carpenter PA, Moravec CK, Kiem H-P, et al. Evaluation of NIH consensus criteria for classification of late acute and chronic GVHD. Blood. 2009;114:702-8.

Lowsky R, Takahashi T, Liu YP, Dejbakhsh-Jones S, Grumet FC, Shizuru JA, et al. Protective conditioning for acute graft-versus-host disease. N Engl J Med. 2005;353:1321-31.

Filipovich AH, Weisdorf D, Pavletic S, Socie G, Wingard JR, Lee SJ, et al. National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report. Biol Blood Marrow Transplant. 2005;11:945-56.

Dignan FL, Clark A, Amrolia P, Cornish J, Jackson G, Mahendra P, et al. Diagnosis and management of acute graft-versus-host disease. Br J Haematol. 2012;158:30-45.

Gale RP, Bortin MM, van Bekkum DW, Biggs JC, Dicke KA, Gluckman E, et al. Risk factors for acute graft-versus-host disease. Br J Haematol. 1987;67:397-406.

Cornejo CM, Kim EJ, Rosenbach M, Micheletti RG. Atypical manifestations of graft-versus-host disease. J Am Acad Dermatol. 2015;72:690-5.

9. Taguchi S, Kawachi Y, Fujisawa Y, Nakamura Y, Furuta J, Otsuka F. Psoriasiform eruption associated with graft-versus-host disease. Cutis. 2013;92:151-3.

Matsushita T, Hasegawa M, Shirasaki F,Fujimoto M, Yamazaki H, Sato S, et al. A case of acute cutaneous graft-versus-host disease mimicking psoriasis vulgaris. Dermatology. 2008;216:64-7.

Goiriz R, Delgado-Jiménez Y, Fernández-Peñas P, Fraga J, García-Diez A, Fernández-Herrera J. Atypical early follicular graft-vs-host disease. Arch Dermatol. 2006;142:1237-8.

Kuskonmaz B, Güçer S, Boztepe G, Cetin M, Uckan D. Atypical skin graft-vs.-host disease following bone marrow transplantation in an infant. Pediatr Transplant. 2007;11:214-6.

How to Cite

1.
Vásquez LA, Mazo A, Ruiz AC. Enfermedad de injerto contra huésped, una presentación inusual. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2017 Jun. 1 [cited 2024 Jul. 3];25(2):162-6. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/13

Downloads

Download data is not yet available.

Published

2017-06-01

How to Cite

1.
Vásquez LA, Mazo A, Ruiz AC. Enfermedad de injerto contra huésped, una presentación inusual. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2017 Jun. 1 [cited 2024 Jul. 3];25(2):162-6. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/13

Issue

Section

Case Report
Crossref Cited-by logo
QR Code
Article metrics
Abstract views
Galley vies
PDF Views
HTML views
Other views