BULLOUS PEMPHIGOID Part 2
DOI:
https://doi.org/10.29176/2590843X.1494Keywords:
Bullous pemphigoid, Subepidermal blisterAbstract
It is an autoimmune subepidermal bullous disease of infrequent presentation, caused by the presence of autoantibodies that are directed against epidermal basement membrane components, known as BPAG1 Y BPAG2. It occurs mainly in older adults associated with high morbidity and mortality. Clinically it is characterized by the appearance of tense blisters on erythematous, edematous and pruritic plaques. For the diagnosis it is important the correlation of the clinic, histopathological evaluation and the study by immunofluorescence. In case of atypical presentations, the diagnosis can become a medical challenge. The treatment is based on the use of immunosuppressants, mainly steroids.
Author Biographies
Juan David Ruiz Restrepo
Patólogo, Docente de Dermatopatología, Universidad de Antioquia, Medellín, Colombia. Patólogo, SURA Ayudas Diagnósticas, Medellín, Colombia.
Melissa Alejandra Quintero Picón
Residente de Patología, Universidad de Antioquia, Medellín, Colombia.
Laura Trujillo Gaviria
Residente de Dermatología, Universidad de Antioquia, Medellín, Colombia.
References
2. Fuertes de Vega I, Iranzo-Fernández P, Mascaró-Galy JM. Penfigoide ampolloso: guía de manejo prác¬tico. Actas Dermosifiliogr. 2014;105(4):328-46. doi: 10.1016/j.ad.2012.10.022.
3. Velásquez MM, Hoyos JG, Castro LA. Enferme¬dades ampollosas autoinmunitarias. Rev Asoc Co¬lomb Dermatol. 2012;127-41.
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