Tumor-like phaeohyphomycosis due to Cladophialophora spp
DOI:
https://doi.org/10.29176/2590843X.1520Keywords:
Phaeohyphomycosis, Immunosuppression, Squamous cell carcinoma, TransplantAbstract
Introduction: The phaeohyphomycosis are mycotic infections, occurring specially in immunocompromised patients, producing many clinical manifestations. Histopathology, cultures, and molecular biology studies are among the diagnosis approach. The treatment includes the combination of systemic antimycotic therapy with surgical interventions.
Case presentation: male patient, 61 years old, diabetic and with kidney transplant; has a history of an ulcered wound over his right knee, unpainful and with secretion, since the last year. On skin biopsy there were observed dematiaceous hyphae, making the presumptive diagnosis of phaeohyphomycosis. After poor clinical evolution using itraconazole and developing systemic symptoms and deep collections, he required the use of amphotericin B and surgical management, obtaining Cladophialophora spp in the culture, confirming the diagnosis. At the time he is receiving voriconazole with satisfying recovery.
Conclusions: we present the case of a tumor-like phaeohyphomycosis in an immunocompromised patient, with poor improvement using systemic therapy only, requiring combination with surgical management.
Author Biographies
Manuel Martínez-Gómez
Médico, residente de dermatología, Sección de dermatología, Facultad de Medicina, Universidad de Antioquia y Hospital Universitario San Vicente Fundación. ORCID https://orcid.org/0000-0001-6593-4275
Miguel Mateo Cuervo-López
Médico, residente de dermatología, Sección de dermatología, Facultad de Medicina, Universidad de Antioquia y Hospital Universitario San Vicente Fundación. ORCID https://orcid.org/0000-0002-6301-6590
Juan David Ruíz-Restrepo
Patólogo, docente de Dermatopatología, Sección de Dermatología, Centro de Investigaciones Dermatológicas CIDERM, Facultad de Medicina, Universidad de Antioquia. ORCID https://orcid.org/0000-0002-2370-2916
María del Pilar Jiménez-Alzate
Médica, doctora en Micología Médica, Departamento de microbiología y parasitología, Facultad de Medicina, Universidad de
Antioquia. ORCID https://orcid.org/0000-0002-7493-4258
References
2. Tambasco D, D'Ettorre M, Bracaglia R, Massi G, Posteraro B, Torelli R, De Simone C, Capizzi R. A Suspected Squamous Cell Carcinoma in a Renal Transplant Recipient Revealing a Rare Cuta¬neous Phaeohyphomycosis by Alternaria infec¬toria. J Cutan Med Surg. 2014; 16(2):131-4. doi: 10.2310/7750.2011.10129
3. Cho Y, Lee J, Chung D. Pedicled chimeric gas¬trocnemius-medial sural artery adipofascial flap for reconstruction of anterolateral defects of the knee. Microsurgery. 2017;37(3):206-11. doi: 10.1002/micr.22436
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