MALIGNANT CUTANEOUS HODGKIN LYMPHOMA: CASE REPORT AND LITERATURE REVIEW
DOI:
https://doi.org/10.29176/2590843X.1523Keywords:
Cutaneous Hodgkin lymphoma, Neoplasm, Reed-Sternberg cell, ImmunohistochemistryAbstract
Hodgkin lymphoma (HL) is a lymphoid neoplasm in which malignant Hodgkin and Reed-Sternberg cells are mixed with a heterogeneous population of non-neoplastic inflammatory cells such as lymphocytes, plasma cells, eosinophils and histiocytes. LH typically presents as painless lymphadenopathy. The skin involvement can be nonspecific or specific; in the nonspecific forms the clinical manifestations are varied and there is no histological evidence of HL in the skin. The specific form is unusual, between 0.5% to 7.5% of cases, in which the skin is infiltrated by neoplastic cells, it is observed in patients in an advanced stage of the disease and represents a poor prognosis. Specific HL skin involvement may be primary or secondary to lymph node disease. We describe the case of an 83-year-old man with classic HL and specific cutaneous involvement, demonstrated by histopathology and confirmed by immunophenotyping.
Author Biographies
Vanessa Pérez-Carrillo
Médica general, Universidad Pontificia Bolivariana, Medellín, Colombia. ORCID https://orcid.org/0000-0002-9600-8597
Delsy Yurledy del Rio-Cobaleda
Médica dermatóloga, Hospital Pablo Tobón Uribe, Medellín, Colombia. ORCID https://orcid.org/0000-0002-8137-2695
Ana Cristina Ruiz-Suárez
Médica dermatopatóloga, Hospital Pablo Tobón Uribe, Medellín, Colombia. ORCID https://orcid.org/0000-0002-0603-4063
Andrea Laverde-Walter
Médica dermatóloga, Universidad CES, Medellín, Colombia. ORCID https://orcid.org/0000-0002-0004-5933
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