Abstract

Senear-Usher syndrome is a localized variant of pemphigus foliaceus, rare, with a chronic course, manifested by well-defined erythematous squamous plaques, with a seborrheic appearance and distribution, which adopts a butterfly-wing pattern resembling cutaneous lupus erythematosus (characteristic in our case) positive Nikolsky sign. With the presence of fragile and fleeting blisters, it does not affect the mucosa, it is a disease of low incidence and represents 0.5 to 3.2 cases per 100,000 inhabitants per year. In ages 15-84 years, on average at 54 years, without predominance of race or sex. We present the case of a 31-year-old male patient, skin phototype V/VI according to Fitzpatrick, with no significant history, presenting bilateral and symmetrical generalized dermatosis beginning in the central facial region characterized by well-defined erythematous plaques with regular borders, with Presence of thick oily yellow scales and bruises on the surface, which spread to other seborrheic areas of the chest, anterior and posterior, exulcerated areas, hyperpigmented macules of variable sizes, pruritic with a 1-year history. A skin biopsy was performed with findings consistent with this disease. Treatment with topical and systemic steroids and immunosuppressants was started with a good response. A case is reported because it is a rare variant of pemphigus foliaceus, so it is important to report this case in Venezuela.