Palpable migratory arciform lesions.
Keywords:
chronic cutaneous lupus erythematosus, lupus erythematosus tumidus, Jessner-Kanof lymphocytic infiltrationAbstract
A 56-year-old man presented with an elevated arciform, annular, erythematous plaque of thirty years on the left side of his upper trunk. The lesion had shown spontaneous resolution with the formation of new arciform or semiannular lesions.
The histological findings showed the epidermis unchanged, in the dermis a dense superficial and deep lymphocytic infiltration, perivascular and periadnexal; Alcian blue staining revealed a significant amount of mucin between collagen bundles, which was negative for Borrelia spp. Immunohistochemistry stains showed than the majority of lymphocytes had a T-cell phenotype, CD3+ CD5+ positive, and CD30- negative. Similar histopathological findings are seen in other pathologies such as Jessner-Kanof lymphocytic infiltration, erythema annular centrifugum, Borrelia spp. infection, polymorphic light eruption, reticular erythematous mucinosis or pseudolymphoma, and, consequently, histological differentiation may be difficult. This case with nonscarring, erythematous, succulent plaques with no surface changes over sun exposed areas, perivascular and periadnexal superficial and deep lymphocytic infiltration, and interstitial mucin deposition is charactetistic of lupus erythematosus tumidus.
Author Biographies
Lucy García
Médica dermatóloga, M.Sc. Ciencias Básicas con énfasis en Inmunología; docente de Dermatología, Universidad del Valle, Cali, Colombia
Sara Lozada
Médica residente, tercer año de Dermatología, Universidad del Valle, Cali, Colombia
Liliana Muñoz
Médica dermatóloga, dermatopatóloga; docente de Dermatología, Universidad del Valle, Cali, Colombia.
References
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