Wells´ syndrome (eosinophilic cellulitis) associated with Helicobacter pylori infection
Keywords:
Wells’ syndrome, eosinophilic cellulitis, eosinophilia, Helicobacter pyloriAbstract
Wells’ syndrome is a rare eosinophilic dermatitis first described 40 years ago, with a wide clinical spectrum and varied histology according to the stage of the cutaneous lesions, associated with numerous endogenous and exogenous factors, including infectious and gastrointestinal diseases.
We present the case of a woman with a 10-day history of edematous, itching and recurrent plaques in limbs with pustules in the right cheek, chest, abdomen and hips. Wells’ syndrome was diagnosed and the following findings were documented: flame figures in the histological sections, negative immunofluorescence for immune complexes and complement deposits, peripheral blood eosinophilia, and Helicobacter pylori infection confirmed by endoscopy and gastric biopsy.
Possible physiopathological mechanisms of a new association with H. pylori are discussed. It may be a coincidence or a possible etiology that should be further investigated.
Author Biographies
Camilo Andrés Morales
Médico dermatólogo, Oficina de Docencia e Investigación, Centro Dermatológico Federico Lleras Acosta, E.S.E., Bogotá, D.C., Colombia; instructor, Facultad de Medicina, Universidad CES, Medellín, Colombia
Andrea Solórzano
Médica, residente de segundo año de Dermatología, Facultad de Medicina, Universidad CES, Medellín, Colombia; Centro Dermatológico Federico Lleras Acosta E.S.E., Bogotá D.C., Colombia
Gerzaín Rodríguez
Médico dermatopatólogo, Facultad de Medicina, Universidad de La Sabana, Chía, Colombia; Centro Dermatológico Federico Lleras Acosta E.S.E. Bogotá, D.C., Colombia
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