Adult Langerhans cell histiocytosis

Authors

  • Lucrecia Infante
  • Juliana Martínez del Sel
  • Estefanía Cesaroni
  • Lucila Donatti
  • Miguel Allevato
  • Mario Marini

Keywords:

Histiocytosis, Langerhans cells, adult Langerhans cell histiocytosis
Abstract Authors References How to Cite Downloads

Abstract

Langerhans cell histiocytosis, previously called histiocytosis X, is a disease characterized by the proliferation of CD1a dendritic cells. Its nature, reactive or neoplastic, is still discussed. Its onset in adulthood is uncommon. Its clinical presentation is varied. Langerhans cell histiocytosis is classified as monosystemic (commitment to a single organ, unifocal or multifocal) and multisystemic (involvement of two or more organs, which is subdivided into low and high risk in relation to the organs involved).
We present a patient with low risk multisystemic adult Langerhans cell histiocytosis (bone and skin involvement only).

Author Biographies

Lucrecia Infante

División de Dermatología, Hospital de Clínicas “José de San Martín”, Buenos Aires, Argentina

Juliana Martínez del Sel

Médica de planta, División de Dermatología, Hospital de Clínicas “José de San Martín” Buenos Aires, Argentina

Estefanía Cesaroni

División de Dermatología, Hospital de Clínicas “José de San Martín”, Buenos Aires, Argentina

Lucila Donatti

Médica de planta, División de Dermatología, Hospital de Clínicas “José de San Martín” Buenos Aires, Argentina

Miguel Allevato

Jefe, División de Dermatología, Hospital de Clínicas “José de San Martín”, Buenos Aires, Argentina

Mario Marini

Médico consultor, Universidad de Buenos Aires Buenos Aires, Argentina

References

1. Aricò M, Girschikofsky M, Generau T, Klersy C, McClain K, Grois N, Emile JF, Lukina E, De Juli E, Danesino C. Langerhans cell histiocytosis in adults. Report from the International Registry of the Histiocyte Society. Eur J Cancer 2003; 39:2341-2348.
2. Donadieu J. Langerhans cell histiocytosis: Portrait of a disease as a rare tumour. Eur J Cancer. 2004;40:1465-6.
3. Aricò M. Langerhans cell histiocytosis in adults: More questions than answers? Eur J Cancer. 2004;40:1467-3.
4. Malpas J. Langerhans cell histiocytosis in adults. Hematol Oncol Clin North Am. 1998;12:259-67.
5. Munn S, Chu A. Langerhans cell histiocytosis of the skin. Hematol Oncol Clin North Am. 1998;12:269-86.
6. Singh A, Prieto V, Czelusta A, Mc Clain K, Duvic M. Adult Langerhans cell histiocytosis limited to the skin. Dermatology 2003; 207:157-161.
7. Egeler RM, Neglia JP, Puccetti DM, Brennan CA, Nesbit ME. Association of Langerhans cell histiocytosis with malignant neoplasms. Cancer. 1993;71:865-73.
8. Stefanato CM, Andersen WK, Calonje E, Swain, FA, Borghi S, Massone L, et al. Langerhans cell histiocytosis in the elderly: A report of three cases. J Am Acad Dermatol. 1998;39:375-8.
9. Mejia R, Dano JA, Roberts R, Wiley E, Cockerell CJ, Cruz PD Jr. Langerhans cell histiocytosis in adults. J Am Acad Dermatol. 1997;37:314-7.
10. Stockschlaeder M, Sucker C. Adult Langerhans cell histiocytosis. Eur J Haematol. 2006;76:363-8.

How to Cite

1.
Infante L, Martínez del Sel J, Cesaroni E, Donatti L, Allevato M, Marini M. Adult Langerhans cell histiocytosis. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Feb. 18 [cited 2024 Jul. 3];20(1):97-100. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/215

Downloads

Download data is not yet available.

Downloads

Published

2019-02-18

How to Cite

1.
Infante L, Martínez del Sel J, Cesaroni E, Donatti L, Allevato M, Marini M. Adult Langerhans cell histiocytosis. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Feb. 18 [cited 2024 Jul. 3];20(1):97-100. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/215

Issue

Vol. 20 No. 1 (2012): January - March

Section

Case Report
QR Code
Article metrics
Abstract views
Galley vies
PDF Views
HTML views
Other views