Spectral analysis of acquired melanocytic lesions
DOI:
https://doi.org/10.29176/2590843X.309Keywords:
Nevus pigmented, spectrum analysis, biopsyAbstract
Introduction: History has established different methods for morphological information of pigmented lesions. The gold standard for diagnosis is biopsy; however, noninvasive optical techniques such as diffuse spectrophotometry reflectance have been developed.
Objective: To characterize acquired melanocytic lesions using diffuse spectrophotometry reflectance.
Materials and methods: We carried out a prospective study, cohort study. The population consisted of 63 patients with acquired melanocytic lesions who consulted the Service of Dermatology, Ciudad Hospitalaria Dr. Enrique Tejera, Valencia, Venezuela. The sampled included 120 nevi classified clinical and histopathological diagnosis. For data collection a Hunterlab MiniScan XE Plus spectrophotometer was used.
Results: There are differences in reflectance between each of the lesions studied. Dysplastic nevi present greater melanin absorption which is related to a deeper lesion on the skin.
Conclusion: Melanocytic nevi studied are characterized by a defined spectral signature. It is recommended to include diffuse spectrophotometry reflectance, as an optional method of diagnosis and monitoring in dermatologic consultation.
Author Biographies
Iriana Álvarez
Médica dermatóloga, Ciudad Hospitalaria Dr. Enrique Tejera, Facultad de Ciencias de la Salud, Universidad de Carabobo, Valencia, Venezuela
Sandra Vivas
Médica dermatóloga; jefe, coordinadora de posgrado de Dermatología, Universidad de Carabobo, Valencia, Venezuela
Aarón Muñoz
Licenciado en Física, maestría y doctorado en Ciencias Básicas con especialidad en Óptica; director general, Centro de Investigaciones Médicas y Biotecnológicas, Universidad de Carabobo, Valencia, Venezuela
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