Leprosy type I reaction mimicking erysipelas

Authors

  • María Jimena Latorre-Gómez
  • Raquel Cristina Maia
  • Brennda Valença
  • Marcos Davi Gomes de Sousa
  • Alice Miranda-Machado
  • Jose Augusto Da Costa Nery

DOI:

https://doi.org/10.29176/2590843X.316

Keywords:

Reversal reaction, leprosy, erysipelas
Abstract Authors References How to Cite Downloads

Abstract

Leprosy is a chronic insidious disease, sometimes interrupted by reactive episodes, characterized by sudden inflammatory reactions, more frequently affecting lepromatous and dimorphic patients. It shows a high incapacitating potential and prognosis improves with early control of the episodes reducing the inflammatory process that attacks preferably peripheral nerves that causes permanent physical disabilities. 
everse reaction (type 1) is associated with sudden increase in Th1 immunity, clinically characterized by exacerbation of old lesions or appearance of new ones. 
We report a case of reversal reaction affecting a multibacillary patient in treatment with multidrug therapy, with systemic involvement besides erythematous, edematous and scaly lesions, whose atypical clinical presentation resembled erysipelas. Biopsy and complementary tests led us to conclude that it was a reverse reaction and started the specific treatment for the reactional episode with satisfactory evolution. 

Author Biographies

María Jimena Latorre-Gómez

Médica dermatóloga, Instituto Carlos Chagas-Policlínica Geral do Río de Janeiro, Rio de Janeiro, Brasil

Raquel Cristina Maia

Médica, Ambulatorio Souza Araújo, Fundación Oswaldo Cruz, Rio de Janeiro, Brasil

Brennda Valença

Médica, Ambulatorio Souza Araújo, Fundación Oswaldo Cruz, Rio de Janeiro, Brasil

Marcos Davi Gomes de Sousa

Medico infectólogo, Instituto Nacional de Infectologia Evandro Chagas; profesor de Enfermedades Infecciosas, Universidad Estácio de Sá, Rio de Janeiro, Brasil

Alice Miranda-Machado

Médica patóloga, doctora en Biología Parasitaria, Laboratorio de Lepra; investigadora asociada, Ambulatorio Souza Araújo, Fundación Oswaldo Cruz, Rio de Janeiro, Brasil

Jose Augusto Da Costa Nery

Médico dermatólogo, magíster en Dermatología, doctorado en Enfermedades Infecciosas y Parasitarias; jefe, Ambulatorio Souza Araújo, Fundación Oswaldo Cruz; jefe, Sector de Dermatología Sanitaria, Instituto de Dermatologia Professor Rubem David Azulay-Santa Casa da Misericórdia do Rio de Janeiro, Brasil; professor titular, Universidade Estácio de Sá; profesor asociado, Policlínica Geral do Rio de Janeiro, Rio de Janeiro, Brasil.

References

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How to Cite

1.
Latorre-Gómez MJ, Maia RC, Valença B, Gomes de Sousa MD, Miranda-Machado A, Da Costa Nery JA. Leprosy type I reaction mimicking erysipelas. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2017 Jul. 1 [cited 2024 Jul. 22];25(3):254-8. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/316

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Published

2017-07-01

How to Cite

1.
Latorre-Gómez MJ, Maia RC, Valença B, Gomes de Sousa MD, Miranda-Machado A, Da Costa Nery JA. Leprosy type I reaction mimicking erysipelas. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2017 Jul. 1 [cited 2024 Jul. 22];25(3):254-8. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/316

Issue

Vol. 25 No. 3 (2017): July – September

Section

Case Report
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