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Keywords:
amyloidosis, multiple myelomaAbstract
Amyloidosis is an uncommon disorder involving a group of diseases characterized by the extracellular deposition of insoluble fibrillar proteins. This mechanism produces different clinical syndromes depending on the location and extent of organ involvement. Mucocutaneous signs of localized amyloidosis, such as lichen amyloidosis and macular and pigmented amyloidosis, are quite different from those of light chain amyloidosis. We report the case of a 68 year old man with primary systemic amyloidosis, severe organ involvement and hemorrhagic cutaneous bullae associated with lytic skull lesions simulating multiple myeloma.
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