Síndrome DRESS
Keywords:
eosinofilia, reacción medicamentosa, síndrome DRESSAbstract
Se trata de una mujer de treinta y dos años, con erupción cutánea asociada con fiebre, congestión faríngea y dolor muscular, quien venía recibiendo sulfazalacina por sacroileítis crónica. Presentaba múltiples adenopatías cervicales y hepatomegalia. El cuadro hemático mostró leucocitosis, linfocitosis y eosinofilia marcada. Transaminasas muy elevadas y biopsia de piel compatible con reacción medicamentosa confirman el diagnóstico de síndrome DRESS.
Author Biographies
Ivonne Constanza Angulo Moreno, Hospital Militar Central
RII Dermatología, Hospital Militar Central, Bogotá, D. C.
Juan Guillermo Chalela Mantilla, Fundación Santafé
Médico Internista-Dermatólogo, Fundación Santafé de Bogotá.
References
1. Sontheimer R, Houpt K. DIDMOHS: a proposed consensus nomenclature for drug-induced delayed multiorgan hypersensitivity syndrome. Arch Dermatol 1998; 134:874-875.
https://doi.org/10.1001/archderm.134.7.874
2. Fernández-Chico N, Bielsa l. Síndrome de hipersensibilidad a fármacos. Piel 2003;18:252-258.
https://doi.org/10.1016/S0213-9251(03)72707-5
3. Baruzzi A, Contin M, Barbara G, Creman C, et al. Drug rash with eosinophilia and systemic symptoms secondary to phenobarbitone. Clin Neuropharmacol 2003; 26:177-178.
https://doi.org/10.1097/00002826-200307000-00004
4. Naisbitt DJ, Farrell J, Wong G, Depta J, et al. Characterization of drug-specific T cells in lamotrigine hypersensitivity. J Allergy Clin lmmunol 2003; 111: 1393-1403.
https://doi.org/10.1067/mai.2003.1507
5. Roujeau JC, Stern RS. Medica! Progress: severe adverse cutaneous reactions to drugs. N Engl J Med 1994; 10:1272-1285.
https://doi.org/10.1056/NEJM199411103311906
6. Mahé E, Bodemer C, Dupic L, Hubert F, et al. Druginduced hypersensitivity syndrome associated with primary Epstein-Barr virus and human herpes virus 6 infections in a child intestinal transplant recipient. Transplantation 2004; 77:479-481.
https://doi.org/10.1097/01.TP.0000102459.25647.C6
7. Hashimoto K, Yasukawa M, Tohyama M. Human herpes virus 6 and drug allergy. Curren! Opinion in Allergy & Clinical lmmunology 2003; 3:255-260.
https://doi.org/10.1097/00130832-200308000-00004
https://doi.org/10.1001/archderm.134.7.874
2. Fernández-Chico N, Bielsa l. Síndrome de hipersensibilidad a fármacos. Piel 2003;18:252-258.
https://doi.org/10.1016/S0213-9251(03)72707-5
3. Baruzzi A, Contin M, Barbara G, Creman C, et al. Drug rash with eosinophilia and systemic symptoms secondary to phenobarbitone. Clin Neuropharmacol 2003; 26:177-178.
https://doi.org/10.1097/00002826-200307000-00004
4. Naisbitt DJ, Farrell J, Wong G, Depta J, et al. Characterization of drug-specific T cells in lamotrigine hypersensitivity. J Allergy Clin lmmunol 2003; 111: 1393-1403.
https://doi.org/10.1067/mai.2003.1507
5. Roujeau JC, Stern RS. Medica! Progress: severe adverse cutaneous reactions to drugs. N Engl J Med 1994; 10:1272-1285.
https://doi.org/10.1056/NEJM199411103311906
6. Mahé E, Bodemer C, Dupic L, Hubert F, et al. Druginduced hypersensitivity syndrome associated with primary Epstein-Barr virus and human herpes virus 6 infections in a child intestinal transplant recipient. Transplantation 2004; 77:479-481.
https://doi.org/10.1097/01.TP.0000102459.25647.C6
7. Hashimoto K, Yasukawa M, Tohyama M. Human herpes virus 6 and drug allergy. Curren! Opinion in Allergy & Clinical lmmunology 2003; 3:255-260.
https://doi.org/10.1097/00130832-200308000-00004
How to Cite
1.
Angulo Moreno IC, Chalela Mantilla JG. Síndrome DRESS. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2005 Oct. 1 [cited 2024 Jul. 3];13(3):235-8. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/540
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Published
2005-10-01
How to Cite
1.
Angulo Moreno IC, Chalela Mantilla JG. Síndrome DRESS. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2005 Oct. 1 [cited 2024 Jul. 3];13(3):235-8. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/540
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