Biología de la cicatrización

  • Adriana Cruz Universidad del Valle
Palabras clave: cicatrización, factores de crecimiento, citoquinas, colágeno

Resumen

Las heridas se clasifican, según el tiempo de evolución en agudas y crónicas, y según su extensión en heridas de espesor parcial y total. El proceso de cicatrización se divide en cuatro fases: l. Hemostasia, donde las plaquetas, y la cascada de coagulación, además de cumplir funciones hemostáticas, aportan una matriz y una serie de moléculas proinflamatorias necesarias para iniciar la reparación. 11. Inflamación, donde polimorfonucleares, monocitos y linfocitos se encargan de debridar y liberar factores de crecimiento y citoquinas para estimular los procesos siguientes. 111. Proliferación, se reemplazan todos los tejidos perdidos en la herida por medio del proceso de re-epitelización, fibroplasia y angiogénesis, y IV. Remodelación, donde se remodela la cicatriz y recupera la fuerza tensil. Para que todos estos procesos puedan ser llevados a cabo exitosamente, se requiere de factores de crecimiento y citoquinas producidos por una gran variedad de células, cada uno con receptores específicos y funciones determinadas que regulan la proliferación, migración y diferenciación celular.

Biografía del autor/a

Adriana Cruz, Universidad del Valle

Residente JI Dermatología, Universidad del Valle, Cali.

Citas

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Cómo citar
1.
Cruz A. Biología de la cicatrización. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 1 de febrero de 2003 [citado 18 de noviembre de 2019];11(1):45-2. Disponible en: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/623

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Publicado
2003-02-01
Sección
Ciencias Básicas