Clinical-pathological correlation of skin biopsies, Dermatology Service. Complejo Hospitalario Dr. Arnulfo Arias Madrid, Panamá, October, 2006-October, 2008
Keywords:
Biopsy, skin, clinical diagnosis, histopathological diagnosisAbstract
Background: Skin biopsy is the most important complementary technique for a dermatologist. Even though a great number of skin biopsies are performed every year in our hospital, to the best of our knowledge, there are no research studies about this matter.
Objetive: To describe the histopathological diagnosis and clinical correlation of skin biopsies performed at the Dermatology Service of the “Complejo Hospitalario Dr. Arnulfo Arias Madrid” between October, 2006, and October, 2008.
Materials and methods: It was a correlational, descriptive, retrospective and transversal study of all skin biopsies that met the selection criteria.
Results: A total of 1,862 biopsies were performed in the study period, though only 1,706 were considered for the study. The other 156 biopsies were excluded because they did not have a clinical diagnosis; 66.5% were form female patients, and 20.6% form patients in the 50-59 age group; 99.6% of the specimens were skin samples and 36% were performed in the head. The biopsy reports had a clinical history (99%), macroscopic description (97.5%), and microscopic description (17.5%). The most frequent clinical and histopathological diagnosis was melanocytic nevi (14%). The histopathological diagnosis correlated with the clinical dermatological diagnosis in 67.5% of the cases.
Conclusion: A total of 1,862 skin biopsies were performed in a two year period by the Dermatology Service of the “Complejo Hospitalario Dr. Arnulfo Arias Madrid”. The histopathological and clinical dermatological diagnoses were the same in 67.5% of the 1,706 biopsies considered for the study.
Author Biographies
José Manuel Ríos
Médico dermatólogo, Caja de Seguro Social, Panamá
Emma Yuil
Médica dermatóloga; delegada CILAD de Panamá; Caja de Seguro Social, Ciudad de Panamá., Panamá
References
2. Verhoeven E, Kraaimaat F, van Weel C, van de Kerkhof P, Duller P, van der Valk P, et al. Skin diseases in family medicine: Prevalence and health care use. Am Fam Med. 2008;6:349-54.
3. Zuber T. Punch biopsy of the skin. Am Fam Phys. 2002;65:1155-8.
4. García A. Dermatología clínica. Quinta edición. Salamanca, España: Gráficas Cervantes, S.A.; 1997. p. 229, 238, 275-8, 280-1, 406, 541, 579.
5. Arenas R. Atlas de dermatología. Tercera edición. México, D.F.: Editorial McGraw-Hill; 2004. p. 491-9.
6. Cormack D. Histología de Ham. Novena edición. México, D.F.: Editorial Harla; 1988. p. 557-9.
7. Navarrete G. Histología de la piel. Rev Fac Med UNAM. 2003;45:130-3.
8. Elder D, Elenitsas R, Johnson BL, Murphy GF, Xu X, Calonje E, et al. Lever´s Histopathology of the Skin. Tenth edition. Philadelphia: Lippincott Williams & Wilkins; 2009.
9. Torres V, Camacho F, Mihm M, Sober A, Sánchez I. Dermatología práctica ibero-latinoamericana. Primera edición. México, D.F.: Editorial Vicente Torres Lozada Nieto, S.A. de C.V.; 2005.
10. Calero G, Ollague J. Dermatología práctica – Actualización y experiencia docente. Segunda edición. Quito, Ecuador: Editorial www.medicosecuador.com; 2007.
11. Naranjo H. Biopsia en dermatología. En: Godoy R, editores. Dermatología – Rondón Lugo. Caracas: Industria Editorial Venezolana; 1995. p. 133-5.
12. Zuber T. Punch biopsy of the skin. Am Fam Phys. 2002;65:1155-8.
13. Alguire P, Mathes B. Skin biopsy techniques for the internist. J Gen Intern Med. 1998;13:48-54.
14. Palomino M. Procedimientos auxiliares de diagnóstico en dermatología. Dermatol. peru. 2002;12:7-14.
15. Regueiro JR, López C, González S, Martínez E. Inmunología: biología y patología del sistema inmune. Tercera edición. Madrid: Editorial Médica Panamericana; 2004.
16. Weedon D. Patología de la piel. Primera edición. Madrid: Editorial Marban Libros; 2002.
17. Sehgal VN, Dogra S, Srivastava G, Aggarwal AK. Psoriasiform dermatoses. Indian J Dermatol Venereol Leprol. 2008;74:94-9.
18. Sa S, Valdez P, Wu J, Jung K, Zhong F, Hall L, et al. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptative immunity in psoriasis. J Immunol. 2007;178:2229-40.
19. Joshi R. Stratum corneum findings as clues to histological diagnosis of pityriasis lichenoides chronica. Indian J Dermatol Venereol Leprol. 2008;74:156-7.
20. Firoz B, Kovich O, Latkowski J. Mycosis fungoides with depigmentation secondary to treatment. Dermatol Online J. 2007;13:18.
21. Sousa FA, Rosa LE. Oral lichen planus: Clinical and histopathological considerations. Braz J Otorhinolaryngol. 2008;74:284-92.
22. Sánchez-Largo ME, Guerra-Tapia A. Lichen striatus in a dark-skinned patient. An Pediatr (Barc.). 2006;65:172-4.
23. Casacci M, Lebas D, Decamps F, Fourrier F, Delaporte E. Toxic epidermal necrolysis due to omeprazole. Eur J Dermatol. 2006;16:699-700.
24. Yi SW, Kim EH, Kang HY, Kim YC, Lee ES. Erythema nodosum: Clinicopathologic correlations and their use in differential diagnosis. Yonsei Med J. 2007;48:601-8.
25. Schwartz RA, Janusz CA, Janniger CK. Seborrheic dermatitis: An overview. Am Fam Physician. 2006;74:125-30.
26. Moore MM, Elpern DJ, Carter DJ. Severe, generalized nummular eczema secondary to interferon alfa-2b plus ribavirin combination therapy in a patient with chronic hepatitis C virus infection. Arch Dermatol. 2004;140:215-7.
27. Kim D, Kang WH. Role of dermal melanocytes in cutaneous pigmentation of stasis dermatitis: A histopathological study of 20 cases. J Korean Med Sci. 2002;17:648-54.
28. Shamim T, Varghese VI, Shameena PM, Sudha S. Pemphigus vulgaris in oral cavity: Clinical analysis of 71 cases. Med Oral Patol Oral Cir Bucal. 2008;13:E622-6.
29. Sánchez-Pérez J, García-Diez A. Pemphigus. Actas Dermosifiliogr. 2005;96:329-56. Correlación clínico-histopatológica de las biopsias de piel
30. Leighty L, Li N, Díaz LA, Liu Z. Experimental models for the autoimmune and inflammatory blistering disease, Bullous pemphigoid. Arch Dermatol Res. 2007;299:417-22.
31. Wollina U. Pyoderma gangrenosum – a review. Orphanet J Rare Dis. 2007;2:19.
32. Rios-Yuil JM, Cachafeiro A. Esclerodermia. Revista Médica de la Caja de Seguro Social. 2006;33:14-8.
33. Ríos-Yuil JM, Santiago D. Hemangiomas Infantiles. Revista Médica de la Caja de Seguro Social. 2007;34:39-43.
34. Ríos-Yuil JM, Montecer B, Surgeon J. Carcinoma cuniculado evolucionando a partir de una verruga plantar: presentación de un caso. Revista Médica de la Caja de Seguro Social. 2008;34:48-55.
35. Crowson AN. Basal cell carcinoma: Biology, morphology and clinical implications. Mod Pathol. 2006;19:S127-47.
36. Domínguez AE. Historia de la dermatopatología en México. Dermatología Rev Mex. 2009;53:40-8.
37. Londoño DA, Mendoza MA, Correa LA, Hoyos JG, Estrada S. Concordancia entre el diagnóstico clínico y el histopatológico en pacientes con lesiones cutáneas. Rev Asoc Colomb Dermatol. 2011;19:119-26.
38. Pérez C, Gómez A, Prieto A, Ferreiro M, Giansante E. Correlación entre diagnóstico clínico e histopatológico en el servicio de dermatología Hospital Universitario de Caracas. Estudio retrospectivo, año 2000. Dermatología Venezolana. 2002;40:48-52.
39. Zapata-Vidal MM, Zuluaga A. Correlación clínico-patológica en entidades dermatológicas. Clínica CES. Medellín 1995- 1997. Revista CES Medicina. 2009;23(Supl.):s49-58.
How to Cite
Downloads
Downloads
Published
How to Cite
Issue
Section
| Article metrics | |
|---|---|
| Abstract views | |
| Galley vies | |
| PDF Views | |
| HTML views | |
| Other views | |
