Correlation between clinical and histopathological diagnoses in patients with skin lesions

Authors

  • David Andrés Londoño
  • María Angélica Mendoza
  • Luis Alfonso Correa
  • Juan Guillermo Hoyos
  • Santiago Estrada

Keywords:

clinic-pathological correlation, dermatology diagnosis, histopathological diagnosis

Abstract

Background: The histopathological examination is an important diagnostic tool in dermatology. However, there are only a few studies evaluating the correlation between clinical and histopathological diagnoses; this is the reason why this research project was conducted.

Objectives: To evaluate the correlation between clinical and histopathological diagnoses and to determine whether improvement is achieved when dermatologists contribute with two or more diagnoses. Patología de la Congregación Mariana were evaluated during the year 2008. Proportional correlation at a confidence interval of 95% (CI95%) was obtained by groups of diagnoses and according to the number of clinical diagnoses.

Results: The proportional correlation between clinical diagnoses and histopathology diagnoses was 63% (CI95%, 59.9 - 66.0) (kappa index=0.55). There was no difference noted in the proportional correlation between groups of histological diagnosis, or according to the number of clinical diagnoses.

Conclusion: The strength of the correlation between clinical and histopathological diagnoses in dermatology was moderate. A greater proportional correlation on larger number of clinical diagnoses was not found.

Author Biographies

David Andrés Londoño

Médico, residente de Dermatología, Universidad de Antioquia, Medellín, Colombia

María Angélica Mendoza

Médica, residente de Patología, Universidad de Antioquia, Medellín, Colombia

Luis Alfonso Correa

Médico patólogo; docente de Dermatopatología, Sección de Dermatología, Grupo de Investigación Dermatológica, GRID, Universidad de Antioquia; patólogo, Laboratorio Clínico, Congregación Mariana, Medellín, Colombia

Juan Guillermo Hoyos

Médico dermatólogo; docente, Sección de Dermatología, Grupo de Investigación Dermatológica, GRID, Universidad de Antioquia; dermatólogo Clínica Diagnóstica Especializada, Congregación Mariana, Medellín, Colombia

Santiago Estrada

Médico microbiólogo clínico; director general, Laboratorio Clínico, Congregación Mariana, Medellín, Colombia

References

1. Olbricht S. Técnicas de biopsia y extirpaciones básicas. En: Bolognia JL, JorizzoJL, Rapini RP, editores. Dermatología. Primera edición. Madrid: Elsevier; 2004. p. 2269-86.

2. Pérez C, Gómez A, Prieto A, Ferreiro M, Giasante E. Correlación entre diagnóstico clínico e histopatológico en el servicio de dermatología Hospital Universitario de Caracas. Estudio retrospectivo, año 2000. Dermatología Venezolana. 2002;40:48-52.

3. Sellheyer K, Bergfeld WF. A retrospective biopsy study of the clinical diagnostic accuracy of common skin diseases by different specialties compared with dermatology. J Am Acad Dermatol. 2005;52:823-30.

4. García J, López A, Acosta J, Pérez-Guillermo M. Rentabilidad diagnóstica de la biopsia cutánea en las enfermedades inflamatorias de la piel. Estudio comparativo según el servicio que la realiza. Actas Dermosifiliogr. 2005;96:92-7.

5. Rajaratnam R, Smith AG, Biswas A, Stephens M. The value of skin biopsy in inflamatory dermatoses. Am J Dermatopathol. 2009;31:350-3.

6. Zapata-Vidal MM, Zuluaga A. Correlación clínico-patológica en entidades dermatológicas. Clínica CES. Medellín 1995- 1997. Revista CES Medicina. 2009;23(Supl.):s49-58.

7. Suhail S, Asad F, Khurshid K, Haroon TS. Correlation between clinical diagnoses and histopathological results in skin diseases: A study of 525 cases. Journal of Pakistan Association of Dermatologists. 2002;12:73-6.

8. Har-Shai Y, Hai N, Taran A, Mayblum S, Barak A, Tzur E, et al. Sensitivity and positive predictive values of presurgical clinical diagnosis of excised benign and malignant skin tumors: A prospective study of 835 lesions in 778 patients. Plast Reconstr Surg. 2001;108:1982-9.

9. Cameron R, Moffatt M, Green AC, Whiteman DC. Diagnostic accuracy in skin cancer clinics: Australian experience. Int J Dermatol. 2006;45:656-60.

10. Heal CF, Raasch BA, Buettner PG, Weedon D. Accuracy of clinical diagnosis of skin lesions. British Journal of Dermatology. 2008;159:661-8.

11. Cepeda S, Pérez A. Estudios de concordancia: intercambiabilidad en sistemas de medición. En: Ruiz A, Morillo L, editores. Epidemiología clínica, investigación clínica aplicada. Primera edición. Bogotá: Editorial Panamericana; 2004. p. 293-307.

12. Zemelman V, Valenzuela C, Fisch F, Road J, Honeyman J. Asertividad en el diagnóstico clínico de los tumores cutáneos. Rev Med Chile. 2003;131:1421-7.

How to Cite

1.
Londoño DA, Mendoza MA, Correa LA, Hoyos JG, Estrada S. Correlation between clinical and histopathological diagnoses in patients with skin lesions. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Mar. 5 [cited 2024 Jul. 3];19(2):119-26. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/372

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Published

2019-03-05

How to Cite

1.
Londoño DA, Mendoza MA, Correa LA, Hoyos JG, Estrada S. Correlation between clinical and histopathological diagnoses in patients with skin lesions. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Mar. 5 [cited 2024 Jul. 3];19(2):119-26. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/372

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Research Article
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