Cryoglubulinemia, case report
Keywords:
cryoglubulinemia, cryoglubulins, cryoglobulinemic vasculitis, blue toe, mielomaAbstract
Cryoglobulins are immunoglobulins that precipitate at low temperatures (below 37 °C, and dissolve again with heat), and are associated with many infections, autoimmune diseases and neoplastic disorders. Symptoms mainly occur through two main mechanisms, vasculitis due to immune complex deposits in vessel walls and tissue ischemia as a direct result of vessel occlusion. Treatment must target the underlying disease, although in some cases it may require immunosuppressor management
Author Biographies
Liliana González
Médica, residente de tercer año, Departamento de Dermatología, Universidad Nacional de Colombia, Bogotá, D.C., Colombia
Elkin Peñaranda
Médico dermatólogo, oncólogo, Hospital Universitario de La Samaritana; docente, Universidad Nacional de Colombia, Bogotá, D.C., Colombia
References
1. Shihabi ZK. Cryoglobulins: An important but neglected clinical test. Ann Clin Lab Sci. 2006;36:395-408.
2. Dammacco F, Sansonno D, Piccoli C, Tucci FA, Racanelli V. The cryoglobulins: an overview. Eur J Clin Invest. 2001;31:628-38.
3. Ramos-Casals M, Robles A, Brito-Zerón P, Nardi N, Nicolás JM, Forns X, et al Life-threatening cryoglobulinemia: clinical and immunological characterization of 29 cases. Semin Arthritis Rheum. 2006;36:189-96.
4. Braun GS, Horster S, Wagner KS, et al. Falta citar tres autores. Cryoglobulinaemic vasculitis: classification and clinical and therapeutic aspects. Postgrad Med J. 2007;83:87-94.
5. Angel OK, June SM, CH Chan. Cryoglobulinaemia: clinical and laboratory Perspectives. Hong Kong Med J. 2008;14:55-9.
6. Mohammed K, Rehman HU. Cryoglobulinaemia. Acta Med Austriaca. 2003;30):65-8.
7. Tedeschi A, Baratè C, Minola E, Morra E Cryoglobulinemia. Blood Rev. 2007;21:183-200.
8. Hirschmann JV, Raugi GJ. Blue (or purple) toe syndrome. J Am Acad Dermatol. 2009;60:1-20.
9. Alpers CE, Smith KD Alpers CE, Smith KD. Cryoglobulinemia and renal disease. Curr Opin Nephrol Hypertens. 2008;17:243-9.
2. Dammacco F, Sansonno D, Piccoli C, Tucci FA, Racanelli V. The cryoglobulins: an overview. Eur J Clin Invest. 2001;31:628-38.
3. Ramos-Casals M, Robles A, Brito-Zerón P, Nardi N, Nicolás JM, Forns X, et al Life-threatening cryoglobulinemia: clinical and immunological characterization of 29 cases. Semin Arthritis Rheum. 2006;36:189-96.
4. Braun GS, Horster S, Wagner KS, et al. Falta citar tres autores. Cryoglobulinaemic vasculitis: classification and clinical and therapeutic aspects. Postgrad Med J. 2007;83:87-94.
5. Angel OK, June SM, CH Chan. Cryoglobulinaemia: clinical and laboratory Perspectives. Hong Kong Med J. 2008;14:55-9.
6. Mohammed K, Rehman HU. Cryoglobulinaemia. Acta Med Austriaca. 2003;30):65-8.
7. Tedeschi A, Baratè C, Minola E, Morra E Cryoglobulinemia. Blood Rev. 2007;21:183-200.
8. Hirschmann JV, Raugi GJ. Blue (or purple) toe syndrome. J Am Acad Dermatol. 2009;60:1-20.
9. Alpers CE, Smith KD Alpers CE, Smith KD. Cryoglobulinemia and renal disease. Curr Opin Nephrol Hypertens. 2008;17:243-9.
How to Cite
1.
González L, Peñaranda E. Cryoglubulinemia, case report. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Mar. 5 [cited 2024 Jul. 3];19(2):175-8. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/378
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Published
2019-03-05
How to Cite
1.
González L, Peñaranda E. Cryoglubulinemia, case report. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Mar. 5 [cited 2024 Jul. 3];19(2):175-8. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/378
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Case Report
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