Cryoglubulinemia, case report
Keywords:
cryoglubulinemia, cryoglubulins, cryoglobulinemic vasculitis, blue toe, mielomaAbstract
Cryoglobulins are immunoglobulins that precipitate at low temperatures (below 37 °C, and dissolve again with heat), and are associated with many infections, autoimmune diseases and neoplastic disorders. Symptoms mainly occur through two main mechanisms, vasculitis due to immune complex deposits in vessel walls and tissue ischemia as a direct result of vessel occlusion. Treatment must target the underlying disease, although in some cases it may require immunosuppressor management
Author Biographies
Liliana González
Médica, residente de tercer año, Departamento de Dermatología, Universidad Nacional de Colombia, Bogotá, D.C., Colombia
Elkin Peñaranda
Médico dermatólogo, oncólogo, Hospital Universitario de La Samaritana; docente, Universidad Nacional de Colombia, Bogotá, D.C., Colombia
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