Patient with livedoid purple plates in legs, and acute myeloid leukemia
Keywords:
Leukostasis, acute myeloid leukemia, diagnosisAbstract
A 66 year-old women with 3 days of fever, livedoid purple plates and pain localized in legs, associated to worsening of the general state. She had a previous diagnosis of acute myeloid leukemia. The skin biopsy showeb vascular occlusion with atypical leukemic blast cells. In order to recognize this rare and progressive condition, seen in myeloproliferative diseases, the clinical presentation and histological manifestations were described.
Author Biographies
María Isabel González
Jefe del Servicio Patología, Hospital Militar Central, Bogotá
Ana María Rebolledo
Dermatóloga, Universidad El Bosque, Bogotá
Dora Luz Fonseca
RIII Dermatología, Universidad Militar Nueva Granada, Bogotá.
References
1. Frankel D. Acral lividosis--a sign of myeloproliferative diseases. Hyperleukocytosis syndrome in chronic myelogenous leukemia. Arch Dermatol. 1987; 123:921- 24.
2. Lowenberg B. Acute Myeloid Leukemia. N Eng J Med. 1999;341:1051-62.
3. Leis F. Management of life-threatening pulmonary leukostasis with single agent imatinib mesylate during chronic myeloid leukemia myeloid blast crisis. Haematologica. 2004;89:ECR30.
4. Stucki, A. Endothelial cell activation by myeloblasts: molecular mechanisms of leukostasis and leukemic cell dissemination. Blood. 2001;97: 2121-9.
5. Majhail N. Acute leukemia with a very high leukocyte count: Confronting a medical emergency. Cleve Clin J Med. 2004; 71: 633-7.
6. Aragona M. Unexpected death by leukostasis and lung leukostasis tumors in acute myeloid leukemia. Minerva Med. 2000;91:229-37.
2. Lowenberg B. Acute Myeloid Leukemia. N Eng J Med. 1999;341:1051-62.
3. Leis F. Management of life-threatening pulmonary leukostasis with single agent imatinib mesylate during chronic myeloid leukemia myeloid blast crisis. Haematologica. 2004;89:ECR30.
4. Stucki, A. Endothelial cell activation by myeloblasts: molecular mechanisms of leukostasis and leukemic cell dissemination. Blood. 2001;97: 2121-9.
5. Majhail N. Acute leukemia with a very high leukocyte count: Confronting a medical emergency. Cleve Clin J Med. 2004; 71: 633-7.
6. Aragona M. Unexpected death by leukostasis and lung leukostasis tumors in acute myeloid leukemia. Minerva Med. 2000;91:229-37.
How to Cite
1.
González MI, Rebolledo AM, Fonseca DL. Patient with livedoid purple plates in legs, and acute myeloid leukemia. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Feb. 1 [cited 2024 Jul. 3];15(3):232-4. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/75
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Published
2019-02-01
How to Cite
1.
González MI, Rebolledo AM, Fonseca DL. Patient with livedoid purple plates in legs, and acute myeloid leukemia. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Feb. 1 [cited 2024 Jul. 3];15(3):232-4. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/75
Issue
Section
Minicases
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