Eritema nodoso leproso en un paciente pediátrico
Palabras clave:
eritema nodoso leproso, reacción tipo II, lepra lepromatosa
Resumen
Se presenta el caso de una paciente de 8 años de edad que cúnsulta por un mes de evolución de lesiones infiltradas, eritematosas, en cara y extremidades, fiebre, síntomas constitucionales y artritis de codo derecho. La histopatología fue compatible con un eritema nodoso leproso.
Referencias bibliográficas
1. Rea TH, Modlin RL. Leprosy. En: Fitzpatrick' s. Dermatology in General Medicine, 1999:2306-2318.
2. Manandhar R, LeMaster J, Roche PW. Risk factors for erythema nodosum leprosum. lnt J Lepra Other Mycobact Dis 1999; 67:270-278.
3. Naafs B. Reactions in leprosy. Biology of the Mycobacteria, London, Academic Press 1989:359-403.
4. Rea TH, Levan NE. Lucio's phenomenon and diffuse non-nodular lepromatous leprosy. Arch Dermatol 1978, 114: 1023-1028.
https://doi.org/10.1001/archderm.114.7.1023
5. Hussain R, Lucas SB, Kifayet A, et al. Clinical and histological discrepancies in diagnosis of erythema nodosum leprosum reactions classified by assessment of acule phase proteins SAA and CRP. lnt J Lepr Other Mycobact Dis 1995; 63:222-230.
6. Moraes MO, Sarno EN, Almeida AS, et al. Cytokine mRNA expression in leprosy: a possible role for interferon-gamma and interleukin-12 in reactions (RR and ENL). Scand J lmmunol 1999; 50:541-549.
https://doi.org/10.1046/j.1365-3083.1999.00622.x
7. Sreenivasan P, Misra RS, Wilfred D, et al. Lepromatous leprosy patients show T-helper 1-like cytokine profile with differential expression of interleukin-1 O during type 1 and 2 reactions. lmmunology 1998; 95:529-536
https://doi.org/10.1046/j.1365-2567.1998.00634.x
8. Sánchez P, Castillo F. lgG antibody subclasses, tumor necrosis factor and IFN-g levels in patients with type 11 lepra reaction on thalidomide treatment. lnt Arch Allergy lmmunol 1998; 116:60-66.
https://doi.org/10.1159/000023926
9. Job CK, Yoder L, Jacobson RR, et al. Skin pigmentation from clofazimine therapy in leprosy patients: a reappraisal. J Am Acad Dermatol 1990; 23:236-241.
https://doi.org/10.1016/0190-9622(90)70204-U
10. Calabresse L, Fleischer AB. Thalidomide: current and potential clinical applications. Am J Med 2000; 108:487-495.
https://doi.org/10.1016/S0002-9343(99)00408-8
2. Manandhar R, LeMaster J, Roche PW. Risk factors for erythema nodosum leprosum. lnt J Lepra Other Mycobact Dis 1999; 67:270-278.
3. Naafs B. Reactions in leprosy. Biology of the Mycobacteria, London, Academic Press 1989:359-403.
4. Rea TH, Levan NE. Lucio's phenomenon and diffuse non-nodular lepromatous leprosy. Arch Dermatol 1978, 114: 1023-1028.
https://doi.org/10.1001/archderm.114.7.1023
5. Hussain R, Lucas SB, Kifayet A, et al. Clinical and histological discrepancies in diagnosis of erythema nodosum leprosum reactions classified by assessment of acule phase proteins SAA and CRP. lnt J Lepr Other Mycobact Dis 1995; 63:222-230.
6. Moraes MO, Sarno EN, Almeida AS, et al. Cytokine mRNA expression in leprosy: a possible role for interferon-gamma and interleukin-12 in reactions (RR and ENL). Scand J lmmunol 1999; 50:541-549.
https://doi.org/10.1046/j.1365-3083.1999.00622.x
7. Sreenivasan P, Misra RS, Wilfred D, et al. Lepromatous leprosy patients show T-helper 1-like cytokine profile with differential expression of interleukin-1 O during type 1 and 2 reactions. lmmunology 1998; 95:529-536
https://doi.org/10.1046/j.1365-2567.1998.00634.x
8. Sánchez P, Castillo F. lgG antibody subclasses, tumor necrosis factor and IFN-g levels in patients with type 11 lepra reaction on thalidomide treatment. lnt Arch Allergy lmmunol 1998; 116:60-66.
https://doi.org/10.1159/000023926
9. Job CK, Yoder L, Jacobson RR, et al. Skin pigmentation from clofazimine therapy in leprosy patients: a reappraisal. J Am Acad Dermatol 1990; 23:236-241.
https://doi.org/10.1016/0190-9622(90)70204-U
10. Calabresse L, Fleischer AB. Thalidomide: current and potential clinical applications. Am J Med 2000; 108:487-495.
https://doi.org/10.1016/S0002-9343(99)00408-8
Cómo citar
1.
Ramírez Escobar AF, Moreno M. LH, Rueda P. R, Jaramillo R, Bravo LE, Victoria Ch. J. Eritema nodoso leproso en un paciente pediátrico. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 1 de febrero de 2002 [citado 3 de octubre de 2023];10(1):703-6. Disponible en: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/622
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