Dark pigmentation of the stratum corneum, What is your diagnosis?

Authors

  • Alejandro Posada

Keywords:

Epidermis, argyria, silver nitrate, skin pigmentation.

Abstract

The pigmentation of the stratum corneum by silver nitrate is a very rare disease caused by particles of silver impregnation, using substances containing silver nitrate, which reacts with sweat chlorine and form silver chloride, which is reduced by ultraviolet light and color is black colloidal particles that persist in the epidermis. The pigmentation occurs shortly after the introduction of metal and disappears weeks after suspension of the product without a specific treatment. Clinically, it may mimic melanocytic lesions, but on histopathology multiple black or dark brown granules are evident in the stratum corneum without alteration in melanocytes.

Author Biography

Alejandro Posada

Médico, residente de cuarto año de Patología Anatómica y Clínica, Universidad Nacional de Colombia, Bogotá, D.C., Colombia

References

1. Utikal J, Thoelke A, Becker JC, Figl R, Goerdt S, Schadendorf D, et al. Local cutaneous argyria mimicking melanoma metastases in a patient with disseminated melanoma. J Am Acad Dermatol. 2006;55(Suppl.5):S92-4.
2. Schanz S, Metzler G. A medical mystery –skin discolorations in a bank employee. N Engl J Med. 2007;356:1455.
3. Weedon D. Cutaneous deposits. In: Weedon D, editor. Weedon’s Skin Pathology. Third edition. London: Churchill Livingstone-Elsevier; 2010. p. 391
4. Massi D, Santucci M. Human generalized argyria: A submicroscopic and X-ray spectroscopic study. Ultrastruct Pathol. 1998;22:47-53.
5. Hristov AC, High WA, Golitz LE. Localized cutaneous argyria. J Am Acad Dermatol. 2011;65:660-1.

How to Cite

1.
Posada A. Dark pigmentation of the stratum corneum, What is your diagnosis?. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Aug. 9 [cited 2024 Jul. 3];22(3):256-7. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/1055

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Published

2019-08-09

How to Cite

1.
Posada A. Dark pigmentation of the stratum corneum, What is your diagnosis?. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 2019 Aug. 9 [cited 2024 Jul. 3];22(3):256-7. Available from: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/1055

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Section

Make the diagnosis yourself. Part 2
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