Granular parakeratosis in children
Keywords:
granular parakeratosis, children, profilaggrin, ColombiaAbstract
Granular parakeratosis is a benign skin disease of unclear etiology which is considered an acquired disorder of keratinization with profilaggrin granules persisting in the stratum corneum. Clinically, it manifests with hyperkeratotic erythematous or brown or brownish papules which may coalesce into plaques with variable hyperpigmentation, located unilaterally or bilaterally in intertriginous areas with chronic irritation (axillary, inframammary, inguinal) or abdominal and lumbosacral areas mainly in areas with folds or occlusion. Itching is variable. Histologically, papillomatosis and acanthosis are found with a thickened parakeratotic stratum corneum and a large number of basophilic granules in the corneocytes. Most reports worldwide have been cases in adults and few cases in children, so we present a case of aranular parakeratosis in a child from Colombia, and a review of the literature.
Author Biographies
Wilson Galvis
Médico, residente de Dermatología, Universidad de Caldas, Manizales, Colombia
Felipe Jaramillo-Ayerbe
Médico dermatólogo, médico dermatopatólogo; director del posgrado de Dermatología, Universidad de Caldas, Manizales, Colombia
Clara Ivonne Soto
Médica dermatóloga, Universidad de Caldas, Manizales, Colombia
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