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Parte II
DOI:
https://doi.org/10.29176/2590843X.31Keywords:
Bowenoid papulosis, nail melanoma, nail plate, Bowen's diseaseAbstract
Nail changes can be a reflection of systemic or local disorders so they should always alert the clinician, who should be interested in finding the cause. Nail folds and the skin surrounding the nail plate should be also evaluated with caution. Patients with immunosuppression have an increased risk of all non-melanoma skin cancers and malignant neoplasms of the nail unit; the most frequent of them is the spiny cell carcinoma of the nail.
Bowenoid papulosis is characterized by the presence of smooth papular lesions and/or multiple verrucous lesions located in genito-inguinal areas and less frequently in extragenital areas. In histopathological evaluation, it is difficult to differentiate it from Bowen's disease. The most characteristic feature of bowenoid papulosis are nuclear mitoses in the same phase, particularly in metaphase and Bowen’s disease is the disordered maturation of keratinocytes, but these findings are not constant.
Many of these lesions remain in situ or have spontaneous regression but because of the low but present risk of transformation to invasive squamous cell carcinoma, a conservative treatment should always be directed, but with the intention of healing. Residual lesions should always be followed-up even more so in immunosuppressed patients in whom this transformation is more likely to occur.
Author Biographies
Catalina Moreno, Universidad de Antioquia, Medellín, Colombia
Médica, residente de Dermatología de tercer año, Centro de Investigaciones Dermatológicas, CIDERM. Universidad de Antioquia, Medellín, Colombia
Juan Carlos Wolf, Universidad de Antioquia, Medellín, Colombia
Médico dermatólogo, dermatopatólogo; docente de Dermatología, Universidad de Antioquia, Medellín, Colombia
Juan Pablo Ospina, Universidad de Antioquia, Medellín, Colombia
Médico patólogo; docente de Dermatopatología, Centro de Investigaciones Dermatológicas, CIDERM. Universidad de Antioquia, Medellín, Colombia
Juan David Ruiz, Universidad de Antioquia, Medellín, Colombia
Médico patólogo; docente de Dermatopatología, Centro de Investigaciones Dermatológicas, CIDERM. Universidad de Antioquia, Medellín, Colombia
Luis Alfonso Correa, Universidad de Antioquia, Medellín, Colombia
Médico patólogo; docente de Dermatopatología, Centro de Investigaciones Dermatológicas, CIDERM. Universidad de Antioquia, Medellín, Colombia
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