Psoriasis en placas secundaria al uso de inhibidores de las tirosina-cinasas: a propósito de un caso y revisión narrativa de la literatura

  • Yusmay Katerine Berbeo-Velásquez Residente de Dermatología, Universidad de Antioquia, Medellín, Antioquia, Colombia.
  • Alejandra Gómez-Ospina Médica general, Universidad de Antioquia, Medellín, Antioquia, Colombia.
  • Gloria Andrea Vargas-Suaza Médica dermatóloga. Docente, Servicio de Dermatología, Universidad de Antioquia. Dermatóloga, Clínica León XVIII, Medellín, Antioquia, Colombia.
Palabras clave: Dasatinib, Imatinib, Leucemia mieloide crónica, Nilotinib, Psoriasis

Resumen

Los inhibidores de las tirosina-cinasas, usados como primera línea para el tratamiento de la leucemia mieloide crónica (LMC)-cromosoma Filadelfia positivo, han sido asociados con el desarrollo de efectos adversos cutáneos, en los cuales se han descrito lesiones compatibles con psoriasis. Se expone el caso de un hombre de 55 años con antecedente de LMC-cromosoma Filadelfia positivo, sin antecedentes personales ni familiares de psoriasis, que desarrolla psoriasis en placas dos años después de iniciar el manejo con este grupo de medicamentos (imatinib y dasatinib). Se realiza una revisión narrativa de la literatura acerca de la psoriasis desencadenada por inhibidores de las tirosina-cinasas y se describen brevemente otros efectos adversos cutáneos ocasionados por estos medicamentos.

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Cómo citar
1.
Berbeo-Velásquez YK, Gómez-Ospina A, Vargas-Suaza GA. Psoriasis en placas secundaria al uso de inhibidores de las tirosina-cinasas: a propósito de un caso y revisión narrativa de la literatura. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 23 de agosto de 2022 [citado 5 de octubre de 2022];30(1):15-8. Disponible en: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/1727

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Publicado
2022-08-23
Sección
Artículo de revisión