Linfoma de células T del adulto por HTLV1 con compromiso cutáneo
Palabras clave:
linfoma, leucemia, infección HTLV-1
Resumen
La leucemia/linfoma de células T del adulto es una alteración maligna linfoproliferativa causada por HTLV-1, con múltiples manifestaciones sistémicas y cutáneas, incluyendo placas, nódulos, lesiones ulceradas y eritrodermia. Presentamos el caso de una mujer con linfoma de células T por HTLV-1 con compromiso cutáneo confirmado por histología e inmunohistoquímica.
Referencias bibliográficas
1. Masahiro A, Motoki K, Katsumi O, Hiroshi I, Hiroaki K, Mitsuru S. New entity, definition and diagnostic criteria of cutaneous adult T-cell leukemia/lymphoma: Human T- lymphotropic virus type 1 proviral DNA load can distinguish between cutaneous and smoldering types. J Dermatol. 2008;35:270-5.
2. Gutiérrez M, Celestino A, Queiroz A, Cuzzi T, Piñero J, de Almeida J. Adult T-cell leukemia/lymphoma associated with HTLV-1 infection in a Brazilian adolescent. Rev Inst Med Trop S Paulo. 2001;43:283-6.
3. Richard F, Jarret A, Williams F. Global epidemic of human T cell limphotropic virus type 1 (HTLV1). J Emerg Med. 2000;18:109-19.
4. Bittencourt A, Barbosa H, Grac M, Farre V. Adul T-cell leukemia/lymphoma (ATL) presenting in the skin: Clinical, histological and inmunohistochemical features of 52 cases. Acta Oncol. 2009;48:598-604.
5. Takashi U. Human T cell leukemia virus type 1 (HTLV1) and human diseases. Annu Rev Immunol. 1997;15:15-37.
6. Nicot C. Current views in HTLV-I-associated adult T-cell leukemia/lymphoma. Am J Hematol. 2005;78:232-9.Lucas C, Gillis K, Ness J, Hammers Y, Crawford D, Kelly D, et al. Adult T-cell leukemia/lymphoma in an adolescent presenting with skin lesions. Pediatr Dermatol. 2008;3:373-7.
7. Shuh M, Beilke M. The human t-cell leukemia virus type 1 (HTLV-1): New insights into the clinical aspects and molecular pathogenesis of adult T-cell leukemia/lymphoma (ATLL) and tropical spastic paraparesis/htlvassociated myelopathy (TSP/HAM). Microsc Res Tech. 2005;68:176-96.
8. Lucas C, Gillis K, Ness J, Hammers Y, Crawford D, Kelly D, et al. Adult T-cell leukemia/lymphoma in an adolescent presenting with skin lesions. Pediatr Dermatol. 2008;3:373-7.
9. Gill P, Harrington W, Kaplan M, Ribeiro R, Bennett J. Treatment of adult T cell leukemia/lymphoma with a combination of interferon alfa and zidovudine. N Engl J Med. 1995;332:1744-8.
2. Gutiérrez M, Celestino A, Queiroz A, Cuzzi T, Piñero J, de Almeida J. Adult T-cell leukemia/lymphoma associated with HTLV-1 infection in a Brazilian adolescent. Rev Inst Med Trop S Paulo. 2001;43:283-6.
3. Richard F, Jarret A, Williams F. Global epidemic of human T cell limphotropic virus type 1 (HTLV1). J Emerg Med. 2000;18:109-19.
4. Bittencourt A, Barbosa H, Grac M, Farre V. Adul T-cell leukemia/lymphoma (ATL) presenting in the skin: Clinical, histological and inmunohistochemical features of 52 cases. Acta Oncol. 2009;48:598-604.
5. Takashi U. Human T cell leukemia virus type 1 (HTLV1) and human diseases. Annu Rev Immunol. 1997;15:15-37.
6. Nicot C. Current views in HTLV-I-associated adult T-cell leukemia/lymphoma. Am J Hematol. 2005;78:232-9.Lucas C, Gillis K, Ness J, Hammers Y, Crawford D, Kelly D, et al. Adult T-cell leukemia/lymphoma in an adolescent presenting with skin lesions. Pediatr Dermatol. 2008;3:373-7.
7. Shuh M, Beilke M. The human t-cell leukemia virus type 1 (HTLV-1): New insights into the clinical aspects and molecular pathogenesis of adult T-cell leukemia/lymphoma (ATLL) and tropical spastic paraparesis/htlvassociated myelopathy (TSP/HAM). Microsc Res Tech. 2005;68:176-96.
8. Lucas C, Gillis K, Ness J, Hammers Y, Crawford D, Kelly D, et al. Adult T-cell leukemia/lymphoma in an adolescent presenting with skin lesions. Pediatr Dermatol. 2008;3:373-7.
9. Gill P, Harrington W, Kaplan M, Ribeiro R, Bennett J. Treatment of adult T cell leukemia/lymphoma with a combination of interferon alfa and zidovudine. N Engl J Med. 1995;332:1744-8.
Cómo citar
1.
Molina AL, Molina V, Arroyave JE, Vásquez LA, Arredondo MI, Ruiz AC. Linfoma de células T del adulto por HTLV1 con compromiso cutáneo. rev. asoc. colomb. dermatol. cir. dematol. [Internet]. 5 de marzo de 2019 [citado 13 de agosto de 2022];19(2):169-71. Disponible en: https://revista.asocolderma.org.co/index.php/asocolderma/article/view/376
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