Linear nevus sebaceous syndrome
DOI:
https://doi.org/10.29176/2590843X.308Keywords:
Nevus, sebaceous of Jadassohn, neurocutaneous syndromes, mosaicism, neoplasmsAbstract
Linear nevus sebaceous syndrome is an infrequent phakomatosis created by a genetic mosaicism which involves HRAS o KRAS autosomal dominant gene mutation.
It is characterized by the coexistence of nevus sebaceous with multisystemic disturbances; thereby, management of the linear nevus sebaceous syndrome requires a multidisciplinary approach. Its diagnosis is clinical; however, occasionally it is difficult due to poor knowledge of the syndrome.
Nevus sebaceous is associated with the development of secondary neoplasms, most of which are benign, and just a few cases may progress to malignant neoplasms.
Author Biographies
Ana María Toro
Médica de planta, Hospital Pablo Tobón Uribe, Medellín, Colombia
Alejandra Ávila
Médica, residente de Dermatología, Universidad Pontificia Bolivariana, Medellín, Colombia
María Isabel Arredondo
Médica dermatóloga, Hospital Pablo Tobón Uribe, Medellín, Colombia
Ana Cristina Ruiz
Médica dermatopatóloga, Hospital Pablo Tobón Uribe, Medellín, Colombia.
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