Henoch-Schönlein purpura in an adult patient: a case report
Keywords:
vasculitis, Henoch-Schönlein purpura, IgAAbstract
Henoch-Schönlein purpura is a systemic vasculitis of small blood vessels. It can affect any organ, mainly skin, joints, kidneys and the gastrointestinal tract.
Henoch-Schönlein purpura is the most common childhood vasculitis, even though adult cases have been described.
We described the case of a 36-year-old female who was diagnosed with type 2 diabetes; she presented with three weeks old itchy blistering lesions in her low extremities. Blood sugar test, lipid profile test and proteinuria tests all showed altered results. The histopathology study revealed an intraepidermal blistering and a leukocitoclastic vasculitis. Direct immunofluorescence showed a perivascular IgA deposit. We diagnosed a Henoch-Schönlein purpura case on an adult patient; therefore, we initiated an oral steroids treatment with 1 mg/kg of
patient for eight weeks. The patient has not presented new skin lesions or renal involvement after treatment though some scarring persisted.
We highlight importance of considering this disease in adults, even though Henoch-Schönlein purpura is an uncommon illness in this age bracket, patients always should be study for systemic involvement and related diseases.
Author Biographies
Karen Zapata
Médica, residente de Dermatología, Universidad del Valle. Cali, Colombia
Ricardo Rueda
Médico dermatólogo, especialista en Dermatopatología, Universidad del Valle, Cali, Colombia
Carlos De La Roche
Médico dermatólogo, Universidad del Valle, Cali, Colombia
References
2. Roberts P, Waller T, Brinker T, Riffe I, Sayre J, Bratton R. Henoch-Schönlein purpura: A review article. South Med J. 2007;8:821-4.
3. Yang Y, Chuang Y, Wang L, Huang H, Gershwin M, Chiang B. The immunobiology of Henoch-Schönlein purpura. Autoimmun Rev. 2008;7:179-84.
4. Smith G. Management of Henoch-Schönlein purpura. Pediatr Child Health. 2008;18:358-63.
5. López M, Cavallasca J, Maliandi M, Nasswetter G. HenochSchönlein purpura in adults. CLINICS. 2008;63:273-6.
6. Zaffanello M, Brugnara M, Franchini M, Fanos V. Adjuvant treatments for nephritis in children. Current Therapeutic Research. 2009;70:254-61.
7. Atkins R, Zimmet P. Diabetic kidney disease: Act now or pay later. Diabetes Res Clin Pract. 2010;90:e54-6.
8. Vupputuri S, Nichols G, Lau H, Joski P, Thorp M. Risk of progression of nephropathy in a population-based sample with type 2 diabetes. Diabetes Res Clin Pract. 2011;91:246-52.
How to Cite
Downloads
Downloads
Published
How to Cite
Issue
Section
| Article metrics | |
|---|---|
| Abstract views | |
| Galley vies | |
| PDF Views | |
| HTML views | |
| Other views | |
