Bilateral vitíligo:
treatment with tacrolimus 0.1% and khellin 3%
Keywords:
Vitíligo, biology, treatmentAbstract
We present the case of a 8-year-old girl, with a two year history of depigmented macules on the face, neck, trunk, and extremities. With a detailed history and physical examination we made the diagnostic of bilateral vitíligo. The treatment with topic tacrolimus 0.1% twice daily and topic khellin 3% combined with natural sunlight for ten minutes once daily was performed. Clinical reponse was documented during clinic visits by physical examination and photographs that showed a rapid response to the treatment and the best repigmentation of the lesions was noted in the face.
Vitíligo is a common disease that affect between 1% and 2% of the world population, the onset of illness occurs before 20 years of age in 50 % of patients, for this reason it can be a significant pediatric problem . The pathogenesis has multiple factors that have been widely studied and there are many mechanisms that have been proposed.
The therapies for childhood onset vitíligo include topical corticosteroids, calcineurin inhibitors, psoralen, PUVA, and UVB-NB.
We describe a patient with vitíligo bilateral who repigmented with tacrolimus combined with khellin and sunlight.
Author Biographies
Natalia Vargas
R II Escuela de Dermatología, Universidad del Valle
Rafael Falabella
Jefe de la Escuela de Dermatología, Universidad del Valle
Jairo Victoria
Docente de Dermatología, Universidad del Valle
References
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