Conceptos básicos, clínicos y terapéuticos de la dermatitis atópica
Palabras clave:
dermatitis atópica, alergia, genética, fisiopatología, tratamientoResumen
La dermatitis atópica (DA) es una enfermedad inflamatoria crónica de la piel, que con frecuencia antecede a la aparición de la rinitis alérgica y el asma. Esta enfermedad genera una alta morbilidad y costos significativos para su atención, puesto que puede afectar hasta el 20% de los niños; se ha observado un aumento en su prevalencia en las dos últimas décadas. Estudios recientes han demostrado la compleja interrelación de factores genéticos, ambientales, farmacológicos e inmunológicos que contribuyen al desarrollo y severidad de la DA. En esta revisión se examinan los mecanismos celulares, moleculares e inmunológicos involucrados en la patogénesis de la DA, así como las diferentes posibilidades terapéuticas para esta enfermedad.
Biografía del autor/a
Liliana María Tamayo Quijano, Universidad de Antioquia
Dermatóloga, Profesora Unidad de Alergias, Facultad de Medicina, Universidad de Antioquia.
Carlos Julio Montoya Guarín, Universidad de Antioquia
Profesor Centro de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia.
Helí Salgado Vélez, Universidad de Antioquia
Pediatra, lnmunólogo, Profesor Departamento de Microbiología y Parasitología,. Facultad de Medicina, Universidad de Antioquia.
Ricardo Cardona Villa, Universidad de Antioquia
Alergólogo, Profesor Unidad de Alergias, Facultad de Medicina, Universidad de Antioquia.
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