Prevalence of polycystic ovary syndrome in colombian women with acne in the adult stage
DOI:
https://doi.org/10.29176/2590843X.1682Keywords:
Acne vulgaris, Hyperandrogenism, Obesity, Polycystic ovary syndromeAbstract
Introduction: Adult female acne (AMA) is an inflammatory disease of the pilosebaceous follicle that occurs after the age of 25, its prevalence has increased in recent years and it has been associated with endocrine diseases such as polycystic ovary syndrome (PCOS). The aim is to determine the prevalence of clinical and biochemical polycystic ovary syndrome in Colombian women with acne in adulthood treated in the dermatology and endocrinology service.
Materials and methods: Cross-sectional descriptive observational study. We included women seen in the dermatology and endocrinology clinic at 2 private clinics in Bucaramanga, Santander during 2021. Demographic, clinical, laboratory and diagnostic data were collected through electronic medical records and those who attended outpatient clinic.
Results: 169 women with acne were included with a mean age of 32.14 ± 5.62 years. 44.97% of the women presented acne for the first time after the age of 25, 34.91% persisted since adolescence and the remaining 20.11% reappeared. 86.39% presented inflammatory acne, preferably on the face, followed by the back and anterior chest. Acne severity was mild in 53.90%. The prevalence of PCOS was 62.13%, where phenotype A predominated.
Conclusions: Acne in adult women is a marker of hyperandrogenism, PCOS being the most frequent cause (6 out of 10). Therefore, the systematic study of PCOS in adult women who consult for acne is suggested.
Author Biographies
Leydi Mantilla, Residente de dermatologia
Médica, residente de Especialización en Dermatología, Universidad Autónoma de Bucaramanga, Floridablanca, Santander, Colombia.
Jessica Inés Vergara-Rueda, Fundación Oftalmológica de Santander
Médica, especialista en Dermatología. Docente, posgrado de Dermatología, Universidad Autónoma de Bucaramanga, Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, Santander, Colombia
Daniela Lynett Barrera, Universidad Autónoma de Bucaramanga
Médica, especialista en Dermatología, Universidad Autónoma de Bucaramanga, Floridablanca, Santander, Colombia.
Xiomara Ríos-Díaz, Universidad Autónoma de Bucaramanga
Médica, especialista en Dermatología, Universidad Autónoma de Bucaramanga, Floridablanca, Santander, Colombia
Edwin Antonio Wandurraga-Sánchez, Fundación Oftalmológica de Santander
Médico, especialista en Endocrinología. Docente, posgrado de Dermatología, Universidad Autónoma de Bucaramanga, Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, Santander, Colombia
Sergio Eduardo Serrano-Gomez, Universidad Autónoma de Bucaramanga
Médico, magíster en Epidemiología, Grupo de Investigación en Epidemiología Clínica, Universidad Autónoma de Bucaramanga, Floridablanca, Santander, Colombia.
References
Bolognia JL, Jorizzo JL, Rapini RP (editores). Dermatología. Madrid: Elsevier España; 2019.
Bagatin E, Proença de Freitas TH, Rivitti-Machado MC, Medeiros B, Nunes S, Dias da Rocha MA. Adult female acne: a guide to clinical practice. An Bras Dermatol. 2019;94(1):62-75. https://doi.org/10.1590/abd1806-4841.20198203
Kamangar F, Shinkai K. Acne in the adult female patient: a practical approach. Int J Dermatol. 2012;51(10):1162-74. https://doi.org/10.1111/j.1365-4632.2012.05519.x
Marks R. Acne and its management beyond the age of 35 years. Am J Clin Dermatol. 2004;5(6):459-62. https://doi.org/10.2165/00128071-200405060-00011
Hazarika N. Acne vulgaris: new evidence in pathogenesis and future modalities of treatment. J Dermatolog Treat. 2021;32(3):277-85. https://doi.org/10.1080/09546634.2019.1654075
Romanska-Gocka K, Wozniak M, Kaczmarek-Skamira E, Zegarska B. The possible role of diet in the pathogenesis of adult female acne. Postepy Dermatol Alergol. 2016;33(6):416-20. https://doi.org/10.5114/ada.2016.63880
Pérez A, Sánchez J. Aspectos diferenciales del acné en la mujer. La piel en la práctica diaria. Piel. 2001;16(6):284-9. https://doi.org/10.1016/S0213-9251(01)72465-3
Rivera R, Guerra A. [Management of Acne in Women Over 25 Years of Age]. Actas Dermosifiliogr. 2009;100(1):33-7.
Carmina E, Dreno B, Lucky WA, George W, Dokras A, Kim J, et al. Female Adult Acne and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee. J Endocr Soc. 2022;6(3):bvac003. https://doi.org/10.1210/jendso/bvac003
Enríquez HT. Acné en la mujer adulta. Piel. 2006;21(7):343-8. https://doi.org/10.1016/S0213-9251(06)72505-9
Ding T, Baio G, Hardiman PJ, Petersen I, Sammon C. Diagnosis and management of polycystic ovary syndrome in the UK (2004-2014): a retrospective cohort study. BMJ Open. 2016;6(7):e012461. https://doi.org/10.1136/bmjopen-2016-012461
Mehta-Ambalal S. Clinical, Biochemical, and Hormonal Associations in Female Patients with Acne: A Study and Literature Review. J Clin Aesthet Dermatol. 2017;10(10):18-24.
Leyden JJ. New understandings of the pathogenesis of acne. J Am Acad Dermatol. 1995;32(5 Pt 3):S15-25. https://doi.org/10.1016/0190-9622(95)90416-6
Aversa A, La Vignera S, Rago R, Gambineri A, Nappi R, Calogero A, et al. Fundamental Concepts and Novel Aspects of Polycystic Ovarian Syndrome: Expert Consensus Resolutions. Front Endocrinol (Lausanne). 2020;11:516. https://doi.org/10.3389/fendo.2020.00516
Ríos X, Mosquera H, Wandurraga EA, Rey JJ, Camacho PA. Estudio de hiperandrogenismo en mujeres colombianas con acné en la etapa adulta [Tesis de grado]. Colombia, Bucaramanga: Universidad Autónoma de Bucaramanga; 2013.
Rivas AM, Vásquez LA, Arredondo MI. Diagnóstico y manejo del síndrome de ovario poliquístico: una perspectiva dermatológica. Rev Asoc Colomb Dermatol. 2010;18(2):78-90.
Zeng X, Xie YJ, Liu YT, Long SL, Mo ZC. Polycystic ovarian syndrome: Correlation between hyperandrogenism, insulin resistance and obesity. Clin Chim Acta. 2020;502:214-21. https://doi.org/10.1016/j.cca.2019.11.003
Bellver J, Rodríguez-Tabernero L, Robles A, Muñoz E, Martínez F, Landeras J, et al. Polycystic ovary syndrome throughout a woman's life. J Assist Reprod Genet. 2018;35(1):25-39. https://doi.org/10.1007/s10815-017-1047-7
Peserico A, Angeloni G, Marini A, Piva G, Panciera A, Suma V. Prevalence of polycystic ovaries in women with acne. Arch Dermatol Res. 1989;281(7):502-3. https://doi.org/10.1007/BF00510088
Bliede K, Roumia A, Khaddam J. Prevalence of Polycystic Ovary Syndrome in Women with Acne Vulgaris. AJRDES. 2020;3(1):5-13.
Shareef A, Prasad P, Kaviarasan P. Prevalence and pattern of PCOS in women presenting with acne, a hospital based prospective observational study. Int J Res Med Sci. 2018;6(3):899-903. https://doi.org/10.18203/2320-6012.ijrms20180611
Zandi S, Farajzadeh S, Safari H. Prevalence of polycystic ovary syndrome in women with acne: Hormone profiles and clinical findings. J Pak Assoc Dermatol. 2010;20(4):194-8.
Maluki AH. The frequency of polycystic ovary syndrome in females with resistant acne vulgaris. J Cosmet Dermatol. 2010;9(2):142-8. https://doi.org/10.1111/j.1473-2165.2010.00500.x
Begum S, Hossain MZ, Rahman F, Banu LA. Polycystic ovarian syndrome in women with acne. J Pak Assoc Dermatol. 2012;22(1):24-9.
Moran C, Tena G, Moran S, Ruiz P, Reyna R, Duque X. Prevalence of polycystic ovary syndrome and related disorders in Mexican women. Gynecol Obstet Invest. 2010;69(4):274-80. https://doi.org/10.1159/000277640
Instituto Colombiano de Bienestar Familiar. ENSIN: Encuesta Nacional de Situación Nutricional; 2015. [Fecha de consulta: marzo 7 de 2022]. Recuperado a partir de: https://bit.ly/2LWnBD9
Baldwin H, Tan J. Effects of Diet on Acne and Its Response to Treatment. Am J Clin Dermatol. 2021;22(1):55-65. https://doi.org/10.1007/s40257-020-00542-y
Conforti C, Agozzino M, Emendato G, Fai A, Fichera F, Marangi GF, et al. Acne and diet: a review. Int J Dermatol. 2022;61(8):930-4. https://doi.org/10.1111/ijd.15862
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