Endocrinología del acné y la unidad pilosebácea
DOI:
https://doi.org/10.29176/2590843X.1624Palabras clave:
Acné, Glándula sebácea, Hiperplasia suprarrenal congénita, Síndrome de Cushing, Síndrome de ovario poliquístico, TestosteronaResumen
El acné es una enfermedad multifactorial con influencia endocrina. El objetivo de este artículo es presentar las bases fisiopatológicas del acné y sus interacciones con el sistema endocrinológico. Se revisan la importancia de las hormonas tradicionalmente descritas, como la testosterona, la dihidrotestosterona y la insulina, como estímulos tróficos para la glándula sebácea. Así mismo, se explora la influencia de otras hormonas tradicionalmente menos asociadas al acné, como el cortisol, la proopiomelanocortina, la prolactina y la hormona de crecimiento, que han probado influenciar la secreción de sebo por la unidad pilosebácea. Finalmente, se describe la interacción de estos fenómenos fisiopatológicos en entidades como el síndrome de ovario poliquístico, la hiperplasia suprarrenal congénita y el síndrome de Cushing.
Biografía del autor/a
Laura Carolina Camacho-Pérez, Dermatóloga, Universidad Nacional de Colombia.
Dermatóloga, Universidad Nacional de Colombia.
Juan José Duque-Ramírez, Unidad de endocrinología, departamento de medicina interna, Universidad Nacional de Colombia.
Unidad de endocrinología, departamento de medicina interna, Universidad Nacional de Colombia.
Paola Hernández-Rúa, Médica General en Hospitalización, Hospital Pablo Tobón Uribe, Medellín
Médica General en Hospitalización, Hospital Pablo Tobón Uribe, Medellín
Héctor José Castellanos-Lorduy, Coordinador, programa curricular de Dermatología, departamento de medicina interna, Universidad Nacional de Colombia.
Coordinador, programa curricular de Dermatología, departamento de medicina interna, Universidad Nacional de Colombia.
Roberto Franco-Vega, Unidad de Endocrinología, departamento de medicina interna, Universidad Nacional de Colombia
Unidad de Endocrinología, departamento de medicina interna, Universidad Nacional de Colombia
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