Síndrome de Stevens-Johnson y necrólisis epidérmica tóxica
Palabras clave:
síndrome de Stevens-Johnson, necrólisis epidérmica tóxica, tratamientoResumen
El síndrome de Stevens-Johnson y la necrólisis epidérmica tóxica son toxicodermias graves que forman parte de un mismo espectro de enfermedad y que, pese a su baja frecuencia, se asocian con una gran morbimortalidad. Aunque su fisiopatología, clasificación y manejo son controvertidos, se sabe que la apoptosis masiva de queratinocitos por diferentes vías se encuentra implicada. No deben confundirse con el eritema multiforme y hasta el momento no se ha demostrado la seguridad y eficacia de los tratamientos, excepto de las medidas de soporte que son el pilar del manejo. A continuación se presenta una revisión de la literatura sobre el síndrome de Stevens-Johnson y la necrólisis epidérmica tóxica.
Biografía del autor/a
Claudia Andrea Hernández
Residente Dermatología, Universidad Pontificia Bolivariana, Medellín, Colombia.
Rodrigo Restrepo
Dermatopatólogo y Docente Universidad Pontificia Bolivariana, Medellín, Colombia.
Milton Mejía
Dermatologo. Universidad Pontificia Bolivariana, Medellín, Colombia.
Referencias bibliográficas
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